Abstract: The present invention provides an Ecoli host cell expressing a recombinant antibody characterized in that the Ecoli host cell has been genetically modified in order to change at least one physical property of one or more Ecoli proteins which in the wild type copurify with said recombinant antibody.
Type:
Application
Filed:
October 15, 2003
Publication date:
March 8, 2007
Applicant:
Celltec R & D Limited
Inventors:
David Humphreys, Andrew Chapman, Martyn Robinson, Mariangela Spitali