Abstract: Recombinant DNA sequences which encode the complete amino acid sequence of a glutamine synthetase, vectors containing such sequences, and methods for their use, in particular as dominant selectable markers, for use in co-amplificiation of non-selected genes and in transforming host cell lines to glutamine independence.
Type:
Grant
Filed:
October 10, 1990
Date of Patent:
June 16, 1992
Assignees:
Celltech Limited, a British Company, The University Court of the University of Glasgow
Inventors:
Richard H. Wilson, Christopher R. Bebbington