Abstract: Benzobicyclooctane compounds, their use in inhibiting cellular events involving TNF-? and IL-8, and in the treatment of inflammation events in general; a combinatorial library of diverse bicyclooctanes and process for their synthesis as a library and as individual compounds.
Type:
Grant
Filed:
December 11, 2001
Date of Patent:
June 14, 2005
Assignee:
Celltech R & D Inc.
Inventors:
Randy W. Jackson, Ihab Darwish, Ted A. Baughman, J. Jeffry Howbert