Patents Assigned to Cellzone Limited
  • Morpholino substituted urea or carbamate derivatives as MTOR inhibitors
    Patent number: 9175011
    Abstract: The invention relates to compounds of formula (I) wherein m, n, R1, T0 and T1 have the meaning as cited in the description and the claims. The compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including said compounds as well as methods of treating mTOR related diseases.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: November 3, 2015
    Assignee: CELLZONE LIMITED
    Inventors: Rosemary Lynch, Andrew David Cansfield, Daniel Paul Hardy, Mihiro Sunose, Adeline Morel, Laura Convery, Rita Adrego
  • Carbon linked modulators of gamma-secretase
    Patent number: 8692017
    Abstract: The present invention relates to compounds of Formula I as shown below, wherein the definitions of A, X, R1, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with ?-secretase activity, including Alzheimer's disease.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: April 8, 2014
    Assignees: Janssen Pharmaceutica, N.V., Cellzone Limited
    Inventors: Chih Yung Ho, Yan Zhang, Svenja Burckhardt, Alison Jones