Patents Assigned to Celmatrix Corporation
  • Patent number: 10342872
    Abstract: A method of inducing hair growth by topical administration of minoxidil is described, including topically applying minoxidil to a skin region susceptible to induction of hair growth, wherein the applied minoxidil is administered to the skin region (i) in a formulation comprising a release composition that mediates a dermal flux of minoxidil of at least 1.5 ?g minoxidil/cm2 skin area/hour for a time of from 17 to 27 hours, at an applied dose of from 2 to 20 mg minoxidil to said skin region, and with a period of from 16 to 30 hours before any subsequent reapplication of the formulation, or (ii) subsequent to administration to the skin region of said release composition so that the sequentially applied minoxidil and release composition together mediate the dermal flux of minoxidil of at least 1.
    Type: Grant
    Filed: February 25, 2018
    Date of Patent: July 9, 2019
    Assignee: CELMATRIX CORPORATION
    Inventor: Shane Malek
  • Patent number: 8444960
    Abstract: A topical administration carrier composition including water, glycerin and polysorbate, suitable for use in formulations with active ingredient compositions containing active ingredients such as minoxidil that are susceptible to systemic penetration, and solvents that are susceptible to evaporative loss, when the active ingredient composition is topically applied to the body. The carrier formulation retards the evaporative losses of the solvent component(s) and systemic migration losses of the active ingredient composition, to provide sustained topical action, in relation to formulations lacking the carrier composition of the invention.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: May 21, 2013
    Assignee: Celmatrix Corporation
    Inventor: Shane Malek
  • Publication number: 20120184575
    Abstract: A topical administration carrier composition including water, glycerin and polysorbate, suitable for use in formulations with active ingredient compositions containing active ingredients such as minoxidil that are susceptible to systemic penetration, and solvents that are susceptible to evaporative loss, when the active ingredient composition is topically applied to the body. The carrier formulation retards the evaporative losses of the solvent component(s) and systemic migration losses of the active ingredient composition, to provide sustained topical action, in relation to formulations lacking the carrier composition of the invention.
    Type: Application
    Filed: February 21, 2012
    Publication date: July 19, 2012
    Applicant: CELMATRIX CORPORATION
    Inventor: Shane Malek
  • Patent number: 8147815
    Abstract: A topical administration carrier composition including water, glycerin and polysorbate, suitable for use with compositions containing active ingredients such as minoxidil that are susceptible to volatilization and transdermal penetration in application to the body. The carrier formulation retards the evaporative and systemic migration losses of the active ingredient composition, to provide sustained topical action, in relation to formulations lacking the components of the inventive composition.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: April 3, 2012
    Assignee: Celmatrix Corporation
    Inventor: Shane Malek
  • Patent number: 8119111
    Abstract: A topical administration carrier composition including water, glycerin and polysorbate, suitable for use in formulations with active ingredient compositions containing active ingredients such as minoxidil that are susceptible to systemic penetration, and solvents that are susceptible to evaporative loss, when the active ingredient composition is topically applied to the body. The carrier formulation retards the evaporative losses of the solvent component(s) and systemic migration losses of the active ingredient composition, to provide sustained topical action, in relation to formulations lacking the carrier composition of the invention.
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: February 21, 2012
    Assignee: Celmatrix Corporation
    Inventor: Shane Malek
  • Patent number: 7749489
    Abstract: A topical administration carrier composition including water, glycerin and polysorbate, suitable for use in formulations with active ingredient compositions containing active ingredients such as minoxidil that are susceptible to systemic penetration, and solvents that are susceptible to evaporative loss, when the active ingredient composition is topically applied to the body. The carrier formulation retards the evaporative losses of the solvent component(s) and systemic migration losses of the active ingredient composition, to provide sustained topical action, in relation to formulations lacking the carrier composition of the invention.
    Type: Grant
    Filed: December 13, 2006
    Date of Patent: July 6, 2010
    Assignee: Celmatrix Corporation
    Inventor: Shane Malek