Patents Assigned to CEMAF
  • Acyl derivatives of melatonin and of melatoninergic analogues and their use as medicinal products
    Patent number: 6140372
    Abstract: The invention relates to derivatives of general formula I ##STR1## as defined in the description. The invention also relates to a process for their preparation and to their therapeutic use, in particular for the treatment of complaints associated with melatonin disorders, and pharmaceutical and cosmetic compositions comprising them.
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: October 31, 2000
    Assignee: Cemaf and Laboratories Besins Isovesco S.A.
    Inventors: Jean-Bernard Fourtillan, Marianne Fourtillan, Jean-Claude Jacquesy, Marie-Paule Jouannetaud, Bruno Violeau, Omar Karam
  • Oxidation derivatives of indolylalkylamines and their use as drugs
    Patent number: 6066663
    Abstract: The invention relates to derivatives of general formula I ##STR1## The invention also relates to pharmaceutical and cosmetic compositions comprising derivatives of general formula I.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: May 23, 2000
    Assignees: CEMAF, Laboratories Besins-Iscovesco S.A.
    Inventors: Jean-Bernard Fourtillan, Marianne Fourtillan, Jean-Claude Jacquesy, Marie-Paule Jouannetaud, Bruno Violeau, Omar Karam
  • Melatonin-antagonist .beta.-carboline derivatives and analogues thereof containing naphthalenic structure, process for their preparation and their use as medicinal products
    Patent number: 6048868
    Abstract: The present invention provides .beta.-carboline derivatives useful as components of cosmetic, medicinal, and pharmaceutical compositions. The medicinal and pharmaceutical compositions can be used to induce hypnotic activity in a subject. Methods of producing the .beta.-carboline derivatives are provided as well.
    Type: Grant
    Filed: March 17, 1998
    Date of Patent: April 11, 2000
    Assignees: Cemaf, Laboratories Besins Iscovesco
    Inventors: J-Bernard Fourtillan, Marianne Fourtillan, Jean-Claude Jacquesy, Marie-Paule Jouannetaud, Bruno Violeau, Omar Karam
  • Acylated derivatives of melationin and its analogues, useful as medicaments
    Patent number: 6004991
    Abstract: The invention relates to derivatives of general formula I ##STR1## as defined in the description. The invention also relates to a process for their preparation and to their therapeutic use, in particular or the treatment of complaints associated with melatonin disorders, and pharmaceutical and cosmetic compositions comprising them.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: December 21, 1999
    Assignee: CEMAF and Laboratoires Besins Iscovesco S.A.
    Inventors: Jean-Bernard Fourtillan, Marianne Fourtillan, Jean-Claude Jacquesy, Marie-Paule Jouannetaud, Bruno Violeau, Omar Karam
  • Melatoninergic agonist spiro ?indolepyrrolidine! derivatives, process for their preparation and their use as medicinal products
    Patent number: 5763471
    Abstract: The present invention relates to spiro?3H-indole-3(2H),3'-pyrrolidine! derivatives of general formula I ##STR1## as defined in the description. The invention also relates to a process for their preparation and to their therapeutic use, in particular for the treatment of complaints associated with melatonin disorders, and to the pharmaceutical and cosmetic compositions comprising them.
    Type: Grant
    Filed: December 11, 1996
    Date of Patent: June 9, 1998
    Assignees: CEMAF, Laboratories Besins Iscovesco
    Inventors: Jean-Bernard Fourtillan, Marianne Fourtillan, Jean-Claude Jacquesy, Marie-Paule Jouannetaud, Bruno Violeau, Omar Karam