Patents Assigned to Centecor, Inc.
  • Tumor necrosis factor inhibitors
    Patent number: 5519000
    Abstract: Peptides which consist of 4-25 amino acids and which bind to tumor necrosis factor-alpha, prevent tumor necrosis factor-alpha from binding to its receptors and inhibit tumor necrosis factor-alpha activity are disclosed. Methods of inhibiting tumor necrosis factor-alpha activity and of treating individuals suffering from tumor necrosis factor-alpha-mediated diseases and disorders are disclosed.
    Type: Grant
    Filed: April 1, 1994
    Date of Patent: May 21, 1996
    Assignee: Centecor, Inc.
    Inventors: George A. Heavner, Marian Kruszynski, Miljenko Mervic, Robert W. Weber
  • Tumor necrosis factor inhibitors
    Patent number: 5506340
    Abstract: Peptides which consist of 4-25 amino acids and which bind to tumor necrosis factor-alpha, prevent tumor necrosis factor-alpha from binding to its receptors and inhibit tumor necrosis factor-alpha activity are disclosed. Methods of inhibiting tumor necrosis factor-alpha activity and of treating individuals suffering from tumor necrosis factor-alpha-mediated diseases and disorders are disclosed.
    Type: Grant
    Filed: April 1, 1994
    Date of Patent: April 9, 1996
    Assignee: Centecor, Inc.
    Inventor: George A. Heavner
  • Tumor necrosis factor inhibitors
    Patent number: 5486595
    Abstract: Peptides which consist of 4-25 amino acids and which bind to tumor necrosis factor-alpha, prevent tumor necrosis factor-alpha from binding to its receptors and inhibit tumor necrosis factor-alpha activity are disclosed. Methods of inhibiting tumor necrosis factor-alpha activity and of treating individuals suffering from tumor necrosis factor-alpha-mediated diseases and disorders are disclosed.
    Type: Grant
    Filed: April 1, 1994
    Date of Patent: January 23, 1996
    Assignee: Centecor, Inc.
    Inventor: George A. Heavner