Patents Assigned to Center for Intelligent Research in Crystal Engineering, S.L.
  • Cocrystals of ubiquinone and compositions comprising them
    Patent number: 11952334
    Abstract: The present invention relates to a cocrystal of ubiquinone and a hydrogen bond donor coformer, to a process for the preparation thereof, and to its use as a medicament or a dietary supplement. The invention also relates to compositions comprising the cocrystal.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: April 9, 2024
    Assignee: CENTER FOR INTELLIGENT RESEARCH IN CRYSTAL ENGINEERING, S.L.
    Inventors: Lidia Bofill Herrera, Dafne De Sande Lopez, Rafel Prohens López, Rafael Barbas Cañero
  • Cocrystals of ubiquinol and compositions comprising them
    Patent number: 11731927
    Abstract: The present invention relates to a cocrystal of ubiquinol and a hydrogen bond donor coformer, to a process for the preparation thereof, and to its use as a medicament or a dietary supplement. The invention also relates to compositions comprising the cocrystal.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: August 22, 2023
    Assignee: CENTER FOR INTELLIGENT RESEARCH IN CRYSTAL ENGINEERING, S.L.
    Inventors: Rafel Prohens López, Rafael Barbas Cañero, Lidia Bofill Herrera, Dafne De Sande López
  • Crystalline forms of beta-sitosterol
    Patent number: 11591363
    Abstract: The present invention relates to a cocrystal of beta-sitosterol or a pharmaceutically acceptable ester thereof or an edible acceptable ester thereof and an organic carboxylic acid coformer, an hydrate crystal form of beta-sitosterol having 1.25 molecules of water per molecule of beta-sitosterol and a combination that comprises a cocrystal of beta-sitosterol and an organic carboxylic acid; and the hydrate crystal form of beta-sitosterol having 1.25 molecules of water per molecule of beta-sitosterol. It also relates to processes for their preparation, and compositions containing them, as well as their use as a medicament or dietary supplement or functional food, and in particular in the prophylaxis and/or treatment of a disease or conditions that involves an alteration of lipid metabolism, circulating levels of lipids in the blood and/or lipid composition in tissues and organs.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 28, 2023
    Assignees: CENTER FOR INTELLIGENT RESEARCH IN CRYSTAL ENGINEERING, S.L., ALIMENTOMICA, S.L.
    Inventors: Rafel Prohens López, Rafael Barbas Cañero, Anna Portell Bueso, Mariona Palou March, Francisca Serra Vich, Andreu Palou March
  • COCRYSTALS OF UBIQUINONE AND COMPOSITIONS COMPRISING THEM
    Publication number: 20210230091
    Abstract: The present invention relates to a cocrystal of ubiquinone and a hydrogen bond donor coformer, to a process for the preparation thereof, and to its use as a medicament or a dietary supplement. The invention also relates to compositions comprising the cocrystal.
    Type: Application
    Filed: August 2, 2019
    Publication date: July 29, 2021
    Applicant: CENTER FOR INTELLIGENT RESEARCH IN CRYSTAL ENGINEERING, S.L.
    Inventors: Lidia BOFILL HERRERA, Dafne DE SANDE LOPEZ, Rafel PROHENS LÓPEZ, Rafael BARBAS CAÑERO
  • CRYSTALLINE FORMS OF BETA-SITOSTEROL
    Publication number: 20200207801
    Abstract: The present invention relates to a cocrystal of beta-sitosterol or a pharmaceutically acceptable ester thereof or an edible acceptable ester thereof and an organic carboxylic acid coformer, an hydrate crystal form of beta-sitosterol having 1.25 molecules of water per molecule of beta-sitosterol and a combination that comprises a cocrystal of beta-sitosterol and an organic carboxylic acid; and the hydrate crystal form of beta-sitosterol having 1.25 molecules of water per molecule of beta-sitosterol. It also relates to processes for their preparation, and compositions containing them, as well as their use as a medicament or dietary supplement or functional food, and in particular in the prophylaxis and/or treatment of a disease or conditions that involves an alteration of lipid metabolism, circulating levels of lipids in the blood and/or lipid composition in tissues and organs.
    Type: Application
    Filed: June 22, 2018
    Publication date: July 2, 2020
    Applicants: Center for Intelligent Research in Crystal Engineering, S.L., AlimenTomica, S.L.
    Inventors: Rafel PROHENS LÓPEZ, Rafael BARBAS CAÑERO, Anna PORTELL BUESO, Mariona PALOU MARCH, Francisca SERRA VICH, Andreu ñ PALOU MARCH