Patents Assigned to Center for Translation Research in cancer
  • Replication protein a binding transcriptional factor (RBT1) and uses thereof
    Patent number: 7094891
    Abstract: The present invention relates to replication protein A (RPA) transcriptional factors. There is provided a nucleotide sequence encoding a replication protein A transcriptional activator 1 (RTB1) and a protein encoded by such a nucleotide sequence. RBT1 has a high activity and is highly transactivated in cancer cells. The sequence may be used to treat neoplastic disorders and in gene therapy.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: August 22, 2006
    Assignee: Center for Translation Research in cancer
    Inventors: Moulay A. Alaoui-Jamali, John Myung-Jae Cho