Abstract: A quick-disconnect coupling for connecting two sections of pipeline or other tubular conduit to each other, including a female coupler carrying a sleeve which is provided with at least one opening therethrough, and which has a locking handle mounted thereon for pivotation about a horizontal axis. The locking handle carries a camming head disposed at a location to project through the opening in the sleeve. The coupling further includes a tubular male adapter dimensioned for insertion into the sleeve and carrying an annular indented, concavely-surfaced groove. The concavely-surfaced groove is disposed on the male adapter at a location to afford alignment with the camming heads carried on the pivotally mounted locking handles. The sleeve also carries at the location of the openings therethrough, a spring-biased safety lever handle which also carries a camming head aligned with the annular groove in the male tubular member.