Patents Assigned to Central Michigan University Board of Trustees
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Patent number: 7915377Abstract: What is disclosed relates to polymers that resist dissolution in organic solvents, are vasodilators, and are tunable explosives. These polymers also form solvent resistant coatings and solvent resistant fibers as well as bonding materials.Type: GrantFiled: January 12, 2010Date of Patent: March 29, 2011Assignee: Central Michigan University Board of TrusteesInventors: Dillip K. Mohanty, Ajit Sharma
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Patent number: 7776997Abstract: What is disclosed relates to polymers that resist dissolution in organic solvents, are vasodilators, and are tunable explosives. These polymers also form solvent resistant coatings and solvent resistant fibers as well as bonding materials.Type: GrantFiled: February 3, 2006Date of Patent: August 17, 2010Assignee: Central Michigan University Board of TrusteesInventors: Dillip K. Mohanty, Ajit Sharma
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Patent number: 7645854Abstract: We report Michael addition products between primary amines and activated ?,?-unsaturated compounds exemplified by diethyl methylenemalonate (DEMM). In various embodiments, the reaction proceeds with high yields in the absence of strong base or Lewis acid catalyst under mild reaction conditions. Depending on the state of steric hindrance in the amine, the reaction products are a double Michael addition product or a so-called vicarious Michael addition reaction product.Type: GrantFiled: March 1, 2006Date of Patent: January 12, 2010Assignee: Central Michigan University Board of TrusteesInventors: Dillip K Mohanty, Zhong-Biao Zhang
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Patent number: 7619054Abstract: Dendrimeric compounds and polymers are also provided wherein the dendrimer core is derived from the Michael reaction products. The branching pattern of the core and the multiplicity of the Michael addition lead to flexibility in designing and synthesizing dendrimeric materials. The Michael addition products are from a reaction between primary amines and activated ?,?-unsaturated compounds exemplified by diethyl methylenemalonate (DEMM). In various embodiments, the reaction proceeds with high yields in the absence of strong base or Lewis acid catalyst under mild reaction conditions. Depending on the state of steric hindrance in the amine, the reaction products are a double Michael addition product or a so-called vicarious Michael addition reaction product.Type: GrantFiled: March 1, 2006Date of Patent: November 17, 2009Assignee: Central Michigan University Board of TrusteesInventors: Dillip K Mohanty, Zhong-Biao Zhang
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Patent number: 7556789Abstract: This invention provides: 1) methods for the identification of broad spectrum holins with a high level of nonenzymatic activity in membranes; 2) conditions required for maintaining and increasing the anti-microbial and anti-pest efficacy of holins in gene fusions; 3) a method for effective targeting of holins expressed in plants through use of leader peptide to direct the holin protein in the plant apoplast and xylem; 4) methods for the control of bacterial and fungal diseases of plants and control of insect and nematode pests that attack plants by expression of gene fusion involving holins, C-terminal additions and leader peptides, and optionally, endolysis; 5) methods for increasing the shelf of cut flowers, and 6) transgenic plants useful for the production of novel antimicrobial proteins based upon holins.Type: GrantFiled: May 14, 2004Date of Patent: July 7, 2009Assignee: Central Michigan University Board of TrusteesInventor: Bradley D. Fahlman
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Patent number: 7432239Abstract: A process for forming a conjugate of a polyoxyalkylene polymer, such as polyethylene glycol, with a compound containing an amine group(s) and/or a sulfide group(s) by reacting the compound with an acrylate terminated polyoxyalkylene, such as polyethylene glycol terminated at one end with acrylate or methacrylate and terminated at the other end with a methoxy group. The reaction is believed to be a Michael addition. When the compound contains primary amine groups, such as the surface primary amine groups of a PAMAM dendrimer, it is usually desirable to convert the primary amine groups to secondary amine groups before the reaction with the acrylate terminated polyoxyalkylene.Type: GrantFiled: May 31, 2005Date of Patent: October 7, 2008Assignee: Central Michigan University Board of TrusteesInventors: Dillip K. Mohanty, Ajit Sharma
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Patent number: 6806223Abstract: The present invention relates to novel singlet oxygen catalysts useful for the production of specialty chemicals. The catalysts include a core material selected from amine coated polymeric beads, amine coated glass beads and multi-generational dendrimers to which condensed carbon molecules are bonded. These catalysts may in turn give rise to other solid phase heterogeneous catalysts useful for stereoselective or regioselective reactions, by way of non-limiting example.Type: GrantFiled: April 19, 2002Date of Patent: October 19, 2004Assignee: Central Michigan University Board of TrusteesInventor: Anton W. Jensen
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Patent number: 3947247Abstract: A stabilizer compound for dyestuffs is prepared by reacting a quaternary heterocyclic nitrogeneous compound and an azo derivative. The reaction is carried out in a non-acid medium. The stabilizers produced from the condensation reaction hereof can be subsequently reacted with suitable dye forming or coupling compounds to form a dyestuff. Dyestuffs produced hereby are useful in dyeing both natural or cellulosic fibers as well as synthetic fibers. The products hereof are useful as printing compositions and evidence excellent shelf life.Type: GrantFiled: October 31, 1973Date of Patent: March 30, 1976Assignee: Central Michigan University Board of TrusteesInventors: Robert E. Kohrman, Pratap G. Phadtare