Patents Assigned to Centrax International, Inc.
  • Epoxyketone compounds for enzyme inhibition
    Patent number: 10787482
    Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof which are useful as inhibitors of proteasomes. The compounds provided herein have improved proteasome potency and selectivity, and increased aqueous solubility, and are useful in treating various conditions or diseases associated with proteasomes.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: September 29, 2020
    Assignee: CENTRAX INTERNATIONAL INC.
    Inventors: Jinfu Yang, Jian James Cen, Xiaoqing Michelle Fan
  • Epoxyketone compounds for enzyme inhibition
    Patent number: 10640533
    Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof which are useful as inhibitors of proteasomes. The compounds provided herein have improved proteasome potency and selectivity, and increased aqueous solubility, and are useful in treating various conditions or diseases associated with proteasomes.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: May 5, 2020
    Assignee: CENTRAX INTERNATIONAL, INC.
    Inventors: Jinfu Yang, Jian James Cen, Xiaoqing Michelle Fan
  • EPOXYKETONE COMPOUNDS FOR ENZYME INHIBITION
    Publication number: 20200087343
    Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof which are useful as inhibitors of proteasomes. The compounds provided herein have improved proteasome potency and selectivity, and increased aqueous solubility, and are useful in treating various conditions or diseases associated with proteasomes.
    Type: Application
    Filed: October 28, 2019
    Publication date: March 19, 2020
    Applicant: CENTRAX INTERNATIONAL, INC.
    Inventors: Jinfu YANG, Jian James CEN, Xiaoqing Michelle FAN
  • EPOXYKETONE COMPOUNDS FOR ENZYME INHIBITION
    Publication number: 20170158734
    Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof which are useful as inhibitors of proteasomes. The compounds provided herein have improved proteasome potency and selectivity, and increased aqueous solubility, and are useful in treating various conditions or diseases associated with proteasomes.
    Type: Application
    Filed: July 14, 2015
    Publication date: June 8, 2017
    Applicant: Centrax International, Inc.
    Inventors: Jinfu YANG, Jian James CEN, Xiaoqing Michelle FAN