Patents Assigned to Centre d'Etudes Experimentales et Cliniques de Physio Biologie de Pharmacologie et d'Eutonologie
  • Patent number: 4906620
    Abstract: New Medicament comprising as active ingredient a N.sup.6 -substituted adenosine of formula I ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are each independently hydrogen or acyl R.sub.4 -CO- in which R.sub.4 is alkyl, aryl, heteroaryl or aralkyl.
    Type: Grant
    Filed: January 13, 1989
    Date of Patent: March 6, 1990
    Assignee: Centre d'Etudes Experimentales et Cliniques de Physio-Biologie de Pharmacologie et d'Eutonologie (CEPBEPE) and Centre National de la Recherche Scientifique
    Inventors: Henri Laborit, Camille George Wemuth
  • Patent number: 4169158
    Abstract: A class of pyridazine derivatives useful as antidepressants and mood elevators when used in medicine of the formula: ##STR1## wherein R.sub.1 is a hydrogen atom or a lower alkyl group;R.sub.2 is an aryl group such as phenyl or naphthyl or substituted phenyl and N is 2 or 3.Y and Z may be the same or different lower alkyl groups or taken together with the nitrogen atom form a heterocyclic ring wherein Z and Y are lower alkylene radicals cyclized in a ring which contains an oxygen atom linked between them and the other ends of the alkylene chain link to the nitrogen atom. The invention also includes non-toxic acid addition salts thereof suitable for pharmaceutical use and methods for their administration and use as therapeutic agents for humans.
    Type: Grant
    Filed: July 29, 1977
    Date of Patent: September 25, 1979
    Assignee: Centre d'Etudes Experimentales et Cliniques de Physio Biologie de Pharmacologie et d'Eutonologie
    Inventor: Henri Laborit
  • Patent number: 4049795
    Abstract: A method for the reversal of shock including hemorrhagic shock and elevation of blood pressure in warm blooded animals including man. An injectable solution of from about 20 to 100 mg 1 kilogram of body weight per day of dihydroxy acetone in a glucose-water solution is administered to the patient. The therapeutic composition is in a dosage unit of from 200 to 1600mg/100 cc of dihydroxy acetone in a hypertonic 5 to 20% glucose solution in water.
    Type: Grant
    Filed: May 13, 1974
    Date of Patent: September 20, 1977
    Assignee: Centre d'Etudes Experimentales et Cliniques de Physio Biologie de Pharmacologie et d'Eutonologie
    Inventor: Henri Laborit