Patents Assigned to Centre de la Recherche de la Scientifique
  • Cell penetrating peptides for intracellular delivery of molecules
    Patent number: 7579318
    Abstract: The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8 (SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: August 25, 2009
    Assignees: Centre de la Recherche de la Scientifique, Panomics, Inc.
    Inventors: Gilles Divita, Frédéric Heitz, Catherine May Morris, Gudrun Aldrian-Herrada