Patents Assigned to CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION
  • Radiopharmaceutical and methods
    Patent number: 11439714
    Abstract: A radiopharmaceutical 177Lu-DOTATATE compound, a composition, and a kit are provided. Further provided are methods of synthesis of a 177Lu-DOTATATE compound and methods of treatment that comprise a 177Lu-DOTATATE compound.
    Type: Grant
    Filed: August 30, 2021
    Date of Patent: September 13, 2022
    Assignee: Centre for Probe Development and Commercialization
    Inventors: Joe McCann, Justyna Kelly, Paul Billone
  • IGF-1R monoclonal antibodies and uses thereof
    Patent number: 11433148
    Abstract: The present invention relates to conjugates including a chelating moiety of a metal complex thereof and a therapeutic or targeting moiety, methods for their production, and uses thereof.
    Type: Grant
    Filed: May 4, 2018
    Date of Patent: September 6, 2022
    Assignee: Centre for Probe Development and Commercialization
    Inventors: Eric Steven Burak, John Richard Forbes, Matthew David Burr Moran, Ryan Wayne Simms, John Fitzmaurice Valliant, Alla Darwish
  • Pharmacokinetic enhancements of bifunctional chelates and uses thereof
    Patent number: 11191854
    Abstract: The present invention relates to conjugates including a chelating moiety of a metal complex thereof and a therapeutic or targeting moiety, methods for their production, and uses thereof.
    Type: Grant
    Filed: May 4, 2018
    Date of Patent: December 7, 2021
    Assignee: Centre for Probe Development and Commercialization
    Inventors: Eric Steven Burak, Stuart James Mahoney, Ryan Wayne Simms, John Fitzmaurice Valliant, Alla Darwish
  • Residualizing linkers and uses thereof
    Patent number: 10758636
    Abstract: The present invention relates to conjugates including a residualizing linker, methods for their production, and uses thereof.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: September 1, 2020
    Assignee: CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION
    Inventors: John Fitzmaurice Valliant, Eric Steven Burak, Neil Grant Cockburn, Alla Darwish, Joel Adamson Drewry, John Richard Forbes, Meiduo Hu, Ryan Wayne Simms, Karin Ann Stephenson, Tao Wu
  • BIOTIN STANNANE FOR HPLC-FREE RADIOIODINATION
    Publication number: 20130261311
    Abstract: The present teachings provide methods that enable the preparation and purification of radioiodinated vectors without the need for HPLC purification, as well as novel precursors which include biotin-like substituents useful in such methods.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 3, 2013
    Applicants: Centre for Probe Development and Commercialization, General Electric Company
    Inventors: Randall Lee Carter, Bruce Fletcher Johnson, Anup Sood, Michael James Rishel, John Fitzmaurice Valliant, Karin Ann Stephenson, Tao Wu, Yang Yang
  • METHOD OF RADIOLABELING
    Publication number: 20120053318
    Abstract: The application describes a method of radiolabeling a molecule comprising reacting the molecule and a radionuclide labeling reagent in an emulsion, such as an oil-in-water emulsion.
    Type: Application
    Filed: September 1, 2011
    Publication date: March 1, 2012
    Applicant: CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION
    Inventors: Ryan Simms, Karin Stephenson, Darren Weaver, John Valliant