Patents Assigned to Centre Henri Becquerrel
  • Methods and kits for classifying diffuse large B-cell lymphomas (DLBCLs) into GCB-DLBCLs or into ABC-DLBCLs
    Patent number: 10519508
    Abstract: The present invention relates to a method for classifying a diffuse large B-cell lymphoma (DLBCL) of a subject into a GCB-DLBCL or into a ABC-DLBCL comprising the step of determining the expression level of 10 genes in a tumor tissue sample obtained from the subject by performing a Reverse Transcriptase Multiplex Ligation dependent Probe Amplification (RT-MLPA) assay wherein the 10 genes are NEK6, IRF4, IGHM, LMO2, FOXP1, TNFRSF9, BCL6, TNFRSF13B, CCND2 and MYBL1.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: December 31, 2019
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Universite de Rouen, Centre Henri Becquerrel
    Inventors: Fabrice Jardin, Philippe Ruminy, Sylvain Mareschal, Vinciane Marchand, Cristina Bagacean