Patents Assigned to CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
  • Patent number: 11744863
    Abstract: Process for preparing a heat-treated pooled human platelet lysate, said process comprising the steps of: a) Providing a pooled human platelet lysate (p HPL), b) Heat-treating the pooled human platelet lysate at a temperature of 50° C. to 70° C. during 20 to 40 minutes, c) Purifying the heat-treated pooled human platelet lysate of step b).
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: September 5, 2023
    Assignees: Centre Hospitalier Regional et Universitaire De Lille (CHRU), UNIVERSITE DE LILLE 2 DROIT ET SANTE, UNIVERSITE DU LITTORAL COTE D'OPALE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), TAIPEI MEDICAL UNIVERSITY
    Inventors: David Devos, Thierry Burnouf, Jean-christophe Devedjian, Ming-Li Chou, Flore Gouel
  • Publication number: 20230207300
    Abstract: A system and method for analyzing volatile organic compounds (VOCs) adsorbed on an adsorbent membrane, by low-temperature plasma and mass spectrometry (LTP-MS). The system includes a receptacle for receiving the adsorbent membrane, a low-temperature plasma ionizer configured to emit a plasma stream in a plasma emission direction, thereby ionizing the VOCs adsorbed by the membrane and forming a VOC-laden ionized gas, and a mass spectrometer for analyzing the ionized VOCs.
    Type: Application
    Filed: May 20, 2021
    Publication date: June 29, 2023
    Applicants: UNIVERSITE DE LILLE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
    Inventors: Isabelle SALZET, Julien FRANCK, Michel SALZET, Flore HERVE
  • Patent number: 11135443
    Abstract: System (1) for treatment by photodynamic therapy comprising an illuminating member (6) which comprises: —a core (35) carrying a light emitting surface (37), and —a hollow sheath (10) adapted to receive the core (35) with the light emitting surface (37) arranged within a balloon (11), the balloon (11) comprising a wall (12) which has an inner surface delimiting an internal space, and an outer surface, the wall (12) being flexible, wherein the internal space of the balloon (11) has a variable capacity, the wall (12) of the balloon (11) being elastically extendible and the balloon (11) presenting a plurality of inflated states in each of which the internal space is filled with a volume of light diffusing solution, and wherein the system further comprises a support provided with a transfer function relating the volume of light diffusing solution of each inflated state with at least one of a corresponding distribution of light power at the outer surface of the wall (12) of the balloon (11) and a corresponding time
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: October 5, 2021
    Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Université de Lille, Centre Hospitalier Regional et Universitaire de Lille (CHRU)
    Inventors: Maximilien Vermandel, Clement Dupont, Nicolas Reyns, Pascal Deleporte, Serge Mordon, Nacim Betrouni
  • Patent number: 10844008
    Abstract: The present invention is directed to novel compounds of Formula (I), pharmaceutically acceptable salts or solvates thereof, and their use.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: November 24, 2020
    Assignees: UNIVERSITE DE LILLE 2 DROIT ET SANTE, CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
    Inventors: Patricia Melnyk, Patrick Vermersch, Pascal Carato, Bénédicte Oxombre-Vanteghem, Héléne Zephir, Marion Donnier-Marechal
  • Patent number: 10561856
    Abstract: The system comprises: —a bundle of light fibers (11) connected to a light-emitting source (8), and both transmitting light inside the light fiber and emitting light toward a treatment volume (V), —a temperature-modifying system attached to the bundle of light fibers (11) to modify temperature in the treatment volume (V).
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: February 18, 2020
    Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Université de Lille 2 Droit et Santé, Centre Hospitalier Regional et Universitaire de Lille (CHRU)
    Inventors: Serge Mordon, Nacim Betrouni, Laurent Mortier
  • Patent number: 10401567
    Abstract: An optical fiber mode scrambler adapted to give a determined bending to an optical fiber inserted in the mode scrambler, the mode scrambler having a general extension direction X, the mode scrambler having a morphology adapted to give the optical fiber a direction along X at the entry of the scrambler, and then to bend the fiber to bring the fiber substantially in the X, Y plan in the ?X and Y directions, before bringing the fiber in a rotation around the X axis substantially in the Y, Z plan in the anti clockwise direction for one full rotation, and then bending the fiber to bring the fiber substantially in the X, Y plan in the ?X and ?Y directions, and then bending the fiber to give the optical fiber a direction along X at the exit of the scrambler.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: September 3, 2019
    Assignees: INSERM ( INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITÉ DE LILLE, CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
    Inventors: Serge Mordon, Pascal Delepôrte, Nacim Betrouni
  • Patent number: 10179761
    Abstract: The present invention is directed to novel compounds of Formula (I), pharmaceutically acceptable salts or solvates thereof, and their use.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: January 15, 2019
    Assignees: UNIVERSITE DE LILLE 2 DROIT ET SANTE, CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
    Inventors: Patricia Melnyk, Patrick Vermersch, Pascal Carato, Bénédicte Oxombre-Vanteghem, Hélène Zephir, Marion Donnier-Marechal
  • Patent number: 10105326
    Abstract: The present invention is directed to pharmaceutical solution comprising at least dopamine for use in treating Parkinson's disease, wherein said pharmaceutical solution is kept under anaerobic conditions from its formulation to its administration.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: October 23, 2018
    Assignees: Centre Hospitalier Regional Et Universitaire De Lille (Chru), Universite De Lille 2 Droit Et Sante, Universite Du Littoral Cote D'Opale
    Inventors: David Devos, Caroline Moreau, Charlotte Laloux, Jean-christophe Devedjian
  • Patent number: 10017476
    Abstract: The present invention relates to the compound having Formula (I) or pharmaceutically acceptable salts or solvates thereof, and its use in treating and/or preventing a Tauopathy.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: July 10, 2018
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU), UNIVERSITE DE LILLE 2 DROIT ET SANTE
    Inventors: Nicolas Sergeant, Luc Buee, Patricia Melnyk, Marion Gay, Nicolas Le Fur