Abstract: Process for preparing a heat-treated pooled human platelet lysate, said process comprising the steps of: a) Providing a pooled human platelet lysate (p HPL), b) Heat-treating the pooled human platelet lysate at a temperature of 50° C. to 70° C. during 20 to 40 minutes, c) Purifying the heat-treated pooled human platelet lysate of step b).
Type:
Grant
Filed:
June 15, 2018
Date of Patent:
September 5, 2023
Assignees:
Centre Hospitalier Regional et Universitaire De Lille (CHRU), UNIVERSITE DE LILLE 2 DROIT ET SANTE, UNIVERSITE DU LITTORAL COTE D'OPALE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), TAIPEI MEDICAL UNIVERSITY
Abstract: A system and method for analyzing volatile organic compounds (VOCs) adsorbed on an adsorbent membrane, by low-temperature plasma and mass spectrometry (LTP-MS). The system includes a receptacle for receiving the adsorbent membrane, a low-temperature plasma ionizer configured to emit a plasma stream in a plasma emission direction, thereby ionizing the VOCs adsorbed by the membrane and forming a VOC-laden ionized gas, and a mass spectrometer for analyzing the ionized VOCs.
Type:
Application
Filed:
May 20, 2021
Publication date:
June 29, 2023
Applicants:
UNIVERSITE DE LILLE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
Inventors:
Isabelle SALZET, Julien FRANCK, Michel SALZET, Flore HERVE
Abstract: System (1) for treatment by photodynamic therapy comprising an illuminating member (6) which comprises: —a core (35) carrying a light emitting surface (37), and —a hollow sheath (10) adapted to receive the core (35) with the light emitting surface (37) arranged within a balloon (11), the balloon (11) comprising a wall (12) which has an inner surface delimiting an internal space, and an outer surface, the wall (12) being flexible, wherein the internal space of the balloon (11) has a variable capacity, the wall (12) of the balloon (11) being elastically extendible and the balloon (11) presenting a plurality of inflated states in each of which the internal space is filled with a volume of light diffusing solution, and wherein the system further comprises a support provided with a transfer function relating the volume of light diffusing solution of each inflated state with at least one of a corresponding distribution of light power at the outer surface of the wall (12) of the balloon (11) and a corresponding time
Type:
Grant
Filed:
March 24, 2017
Date of Patent:
October 5, 2021
Assignees:
INSERM (Institut National de la Santé et de la Recherche Médicale), Université de Lille, Centre Hospitalier Regional et Universitaire de Lille (CHRU)
Abstract: The system comprises: —a bundle of light fibers (11) connected to a light-emitting source (8), and both transmitting light inside the light fiber and emitting light toward a treatment volume (V), —a temperature-modifying system attached to the bundle of light fibers (11) to modify temperature in the treatment volume (V).
Type:
Grant
Filed:
November 25, 2014
Date of Patent:
February 18, 2020
Assignees:
INSERM (Institut National de la Santé et de la Recherche Médicale), Université de Lille 2 Droit et Santé, Centre Hospitalier Regional et Universitaire de Lille (CHRU)
Abstract: An optical fiber mode scrambler adapted to give a determined bending to an optical fiber inserted in the mode scrambler, the mode scrambler having a general extension direction X, the mode scrambler having a morphology adapted to give the optical fiber a direction along X at the entry of the scrambler, and then to bend the fiber to bring the fiber substantially in the X, Y plan in the ?X and Y directions, before bringing the fiber in a rotation around the X axis substantially in the Y, Z plan in the anti clockwise direction for one full rotation, and then bending the fiber to bring the fiber substantially in the X, Y plan in the ?X and ?Y directions, and then bending the fiber to give the optical fiber a direction along X at the exit of the scrambler.
Type:
Grant
Filed:
February 3, 2017
Date of Patent:
September 3, 2019
Assignees:
INSERM ( INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITÉ DE LILLE, CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
Abstract: The present invention is directed to pharmaceutical solution comprising at least dopamine for use in treating Parkinson's disease, wherein said pharmaceutical solution is kept under anaerobic conditions from its formulation to its administration.
Type:
Grant
Filed:
May 12, 2015
Date of Patent:
October 23, 2018
Assignees:
Centre Hospitalier Regional Et Universitaire De Lille (Chru), Universite De Lille 2 Droit Et Sante, Universite Du Littoral Cote D'Opale
Inventors:
David Devos, Caroline Moreau, Charlotte Laloux, Jean-christophe Devedjian
Abstract: The present invention relates to the compound having Formula (I) or pharmaceutically acceptable salts or solvates thereof, and its use in treating and/or preventing a Tauopathy.
Type:
Grant
Filed:
March 16, 2016
Date of Patent:
July 10, 2018
Assignees:
INSERM (Institut National de la Sante et de la Recherche Medicale), CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU), UNIVERSITE DE LILLE 2 DROIT ET SANTE
Inventors:
Nicolas Sergeant, Luc Buee, Patricia Melnyk, Marion Gay, Nicolas Le Fur