Abstract: The present invention relates to the use of compounds for the prevention and treatment of diseases whose initiation and/or evolution relates to the production and effects of reactive oxygen species (ROS) of mitochondrial origin.
Type:
Grant
Filed:
May 13, 2020
Date of Patent:
May 3, 2022
Assignees:
OP2 DRUGS, CENTRE HOSPITALIER UNIVERSITAIRE DE BOURDEAUX, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE BORDEAUX
Inventors:
Philippe Diolez, Dominique Detaille, Frédéric Marin, Olivier Petitjean
Abstract: The present invention relates to the use of compounds for the prevention and treatment of diseases whose initiation and/or evolution relates to the production and effects of reactive oxygen species (ROS) of mitochondrial origin.
Type:
Grant
Filed:
March 28, 2019
Date of Patent:
May 19, 2020
Assignees:
OP2 DRUGS, CENTRE HOSPITALIER UNIVERSITAIRE DE BOURDEAUX, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE BORDEAUX
Inventors:
Philippe Diolez, Dominique Detaille, Frédéric Marin, Olivier Petitjean
Abstract: An ultrasound cardiac stimulation system includes: a system for measuring the heart electrical activity; a system for generating a beam of focussed ultrasound signals focussed on a targeted zone, the signals being calibrated to generate electrical stimulation in a zone of the heart, the beam generation being synchronised with a first selected time of the electrocardiogram, the generation of the beam corresponding to a pulse with a duration of less than 80 ms; a system for locating the targeted zone coupled with a system for positioning the system for generating the focussed beam to control the beam of focussed ultrasound signals in the targeted zone, the location system being synchronised with the system for generating the beam of focussed signals; a single monitoring system following in real time a temperature and tissue deformation in the targeted zone, the monitoring system taking measurements in synchronisation with the rhythm of the electrocardiogram.
Type:
Application
Filed:
September 1, 2015
Publication date:
October 5, 2017
Applicants:
CENTRE HOSPITALIER UNIVERSITAIRE DE BOURDEAUX, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE DE BORDEAUX
Inventors:
Fabrice MARQUET, Pierre BOUR, Bruno QUESSON, Fanny VAILLANT, Remi DUBOIS