Patents Assigned to CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
  • Patent number: 10466255
    Abstract: A method for predicting the risk of developing a disseminated infection in a patient admitted to intensive care having no clinical symptoms of such infection includes: determining a first dose of gelsolin G1 in a biological sample from the patient originating from a first sample taken at time T1, carried out between the day of intensive care admission and 48 hours afterward; determining a second dose of gelsolin G2 in a biological sample from the patient originating from a second sample taken at time T2, carried out two to three days after the first sampling; calculating the variation between the dose of gelsolin G2 and the dose of gelsolin G1, giving a ? value; and comparing the ? value to a threshold value S determined beforehand from two patient populations admitted to intensive care, one not having developed a disseminated infection and the other having developed such an infection.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: November 5, 2019
    Assignees: BIOMERIEUX, HOSPICES CIVILS DE LYON, CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
    Inventors: Bernard Allaouchiche, Karim Asehnoune, Marilyne Dupin, Tanguy Fortin, Aurélie Gouel-Cheron, Audrey Larue-Triolet, Guillaume Monneret, Alexandre Pachot, Sylvie Pons, Antoine Roquilly, Fabienne Venet
  • Publication number: 20190240406
    Abstract: A method for controlling an insulin injection device and a system for delivering insulin in a patient in need thereof. The method includes the steps of defining a time interval; receiving the level of blood glucose; computing an insulin dose to be injected in the next time interval, and transmitting the computed insulin dose to be injected to the insulin injection device.
    Type: Application
    Filed: October 13, 2017
    Publication date: August 8, 2019
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ÉCOLE CENTRALE DE NANTES, CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES, UNIVERSITÉ DE NANTES, CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET), INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)
    Inventors: Claude MOOG, Nicolas MAGDELAINE, Santiago RIVADENEIRA, Lucy CHAILLOUS, Michel KREMPF
  • Patent number: 10155001
    Abstract: The invention relates to a Rac1 inhibitor for use as bronchodilator in a patient in need thereof. The invention provides a Rac1 inhibitor for use in a method for inducing bronchodilation in a patient in need thereof. The invention also relates to a Rac1 inhibitor for use in a method for reducing AHR in a patient in need thereof.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: December 18, 2018
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Centre National de la Recherche Scientifique (CNRS), Universite de Nantes, Centre Hospitalier Universitaire de Nantes
    Inventors: Vincent Sauzeau, Gwennan Andre, Gervaise Loirand, Antoine Magnan, David Lair
  • Patent number: 9974763
    Abstract: A composition for treating Neurodegenerative Diseases with Parkinsonian Syndromes in a subject in need thereof, wherein the composition includes an effective amount of a modulator of a chloride transporter.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: May 22, 2018
    Assignees: B&A THERAPEUTICS, CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE D'AUX MARSEILLE, UNIVERSITE DE NANTES
    Inventors: Yehezkel Ben-Ari, Nathalie Dehorter, Philippe Damier, Constance Hammond
  • Publication number: 20180095094
    Abstract: A method for predicting the risk of developing a disseminated infection in a patient admitted to intensive care having no clinical symptoms of such infection includes: determining a first dose of gelsolin G1 in a biological sample from said patient originating from a first sample taken at time T1, carried out between the day of intensive care admission and 48 hours afterward; determining a second dose of gelsolin G2 in a biological sample from said patient originating from a second sample taken at time T2, carried out two to three days after the first sampling; calculating the variation between the dose of gelsolin G2 and the dose of gelsolin G1, giving a ? value; and comparing the ? value to a threshold value S determined beforehand from two patient populations admitted to intensive care, one not having developed a disseminated infection and the other having developed such an infection.
    Type: Application
    Filed: May 11, 2016
    Publication date: April 5, 2018
    Applicants: BIOMÉRIEUX, HOSPICES CIVILS DE LYON, CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
    Inventors: Bernard ALLAOUCHICHE, Karim ASEHNOUNE, Marilyne DUPIN, Tanguy FORTIN, Aurélie GOUEL-CHERON, Audrey LARUE-TRIOLET, Guillaume MONNERET, Alexandre PACHOT, Sylvie PONS, Antoine ROQUILLY, Fabienne VENET
  • Patent number: 9714261
    Abstract: An ionic liquid supported organotin reagent of formula (I) A process for manufacturing the ionic liquid supported organotin reagent of formula (I), a process for manufacturing an halogenated or radio-halogenated compound using compound of formula (I), a device for implementing the halogenating process and a kit including the compound of formula (I) are also described.
    Type: Grant
    Filed: January 7, 2015
    Date of Patent: July 25, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE NANTES, UNIVERSITE D' ANGERS, UNIVERSITE DU MAINE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
    Inventors: Stephanie Legoupy, Djibril Faye, Jean-Francois Gestin, Holisoa Rajerison, Alain Faivre-Chauvet, Fabien Boeda