Patents Assigned to CENTRE NATIONAL DE LA RECHARCHE SCIENTIFIQUE
  • Cyclic GMP-chelating peptides for subcellular targeting
    Patent number: 11512294
    Abstract: The disclosure pertains to the field of molecular means capable of binding to, and preferably of chelating, cGMP, appropriate for use in vitro or in vivo and preferably capable of targeting specific cellular compartments. The polypeptides of the disclosure comprise a chimeric construction derived from the N terminus part of PKG-I? and PKG-I?, and the two cGMP binding sites of the wild type PKG.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: November 29, 2022
    Assignees: SORBAOONE UNIVERSITE, CENTRE NATIONAL DE LA RECHARCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET LA RECHERCHE MEDICALE (INSERM)
    Inventors: Xavier Nicol, Oriol Ros Torres
  • Mutant human and simian immunodeficiency virus ENV proteins with reduced immunosuppressive properties
    Patent number: 9682137
    Abstract: A pharmaceutical composition includes, as active substance a mutated lentiviral ENV protein, substantially devoid of immunosuppressive properties or a variant of the mutated lentiviral ENV protein or a fragment of the above proteins, in association with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: June 20, 2017
    Assignees: VIROXIS SAS, CENTRE NATIONAL DE LA RECHARCHE SCIENTIFIQUE, UNIVERSITE PARIS-SUD XI, INSTITUT GUSTAVE ROUSSY
    Inventor: Thierry Heidmann