Abstract: The present invention relates to a polymer foam, said polymer foam comprising pores forming an open-cell polymer foam, said polymer foam comprising a supramolecular gel inside pores, and said polymer foam comprising at least one enzyme. The present invention relates to a supramolecular gel; its preparation and its applications, notably in chemical synthesis and kinetic resolution, in particular of organic compounds. The present invention also relates to flow chemistry.

Abstract: An optical element is provided. The optical element may comprise a material, the material being a matrix and a set of particles included in the matrix, the material having a molar fraction of SiO2 higher than or equal to 65 percent, each particle having a dimension smaller than or equal to 80 nanometers.

Abstract: A real-time diagnosis aid method including: (a) providing a decision-support system for autonomous medical diagnosis to a user of a medical system, the system comprising a display module and software modules embodied on a computer readable medium; (b) generating on the display module an ordered list of diagnostic clues to look at by the user according to the diagnostic clues already filled in as absent or present, the ordered list being based on the relevance of looking at respective diagnostic clues to quickly lead to a diagnosis by the user; (c) receiving from the user, information on presence or absence of one or more diagnosis clues listed in the ordered list; and (d) processing the received information to update the ordered list and provide on the display module an indication of the probability of each possible diagnosis.

Abstract: The invention relates to the use of a ternary alloy having the formula SixTiyNiz, wherein x, y and z are natural numbers, for use in electrolysis and photoelectrolysis, in particular photo-oxidation of water. One aspect of the invention relates to a method for the manufacture of an electrode, the method comprising a step of heating a carrier comprising a surface having a layer of silicon on which a layer of TiO2 is disposed, the layer of TiO2 being covered with a layer of NiO; the heating step being carried out at a temperature above 1,000° C., and preferably between 1,150° C. and 1,250° C. The invention also relates to an electrode comprising a carrier, said electrode having either: an outer surface on which particles of a ternary alloy having the formula SixTiyNiz are positioned, wherein x, y and z are natural numbers, and wherein the particles form protrusions; or an outer surface consisting of a layer of said alloy, the layer comprising protrusions.

Abstract: A hook fusion protein, which includes a hook domain and at least one cytoplasmic carboxyl endoplasmic reticulum (ER) retention signal and/or at least one cytoplasmic amino terminal endoplasmic reticulum (ER) retention signal; wherein the hook fusion protein is a soluble protein that localizes in the cytoplasm. Also, a nucleic acid system for intracellular targeting control including a nucleic acid encoding a target fusion protein including a hook fusion protein, and a nucleic acid encoding a target fusion protein including a hook-binding domain; wherein the target fusion protein is a membrane protein; and wherein the hook fusion protein localizes in the ER when bound to the target fusion protein. Additionally, a vector system, viral particle system, host cell and kit include these nucleic acids. Further, the vector system, viral particle system, host cell or kit for use as a medicament, in particular for immunotherapy.

Abstract: The present disclosure relates to a method for the preparation, from a mixture comprising (i) plant proteins, (ii) one or more plant tanning agents, (iii) one or more plasticizers, of a biobased material that may resemble animal leather.

Abstract: A non-invasive method for measuring a physical quantity representative of the elasticity of a material, including: determining the phase velocities of the fundamental mode of the various components of a shear wave generated at the surface of the material, along a measurement axis, the set of pairs, each formed by a frequency f, and the phase velocity Vi of the fundamental mode determined for the frequency fi, forming a dispersion curve of the fundamental mode in a measurement direction parallel to the measurement axis, wherein the index i is an order number of the frequency fi and of the phase velocity Vi, and transforming the dispersion curve into a profile of phase velocities as a function of depth, the phase velocity at a given depth being a physical quantity representative of the elasticity of a material at the depth.

Abstract: An acoustic treatment grid intended to be mounted inside or at the outlet of a duct of a bleed valve of a turbomachine of an aircraft intended to convey a gas flow, the grid comprising a perforated plate and circular orifices traversing the perforated plate along a first direction, the orifices having a diameter and a geometrical center. Each orifice is separated from an adjacent orifice by a space, the length of which is equal to the product of the diameter of said orifice and a spacing coefficient of a value between 1.1 and 6.

Abstract: The biotelemetry device (100) comprises a microcontroller (101) for generating an electrical setpoint signal (CS); a radio antenna (103) for transmitting an electromagnetic wave (EMS) by converting an incident electrical signal (IS); a radiofrequency circuit (102), interconnected between the microcontroller (101) and the radio antenna (103). The radio antenna (103) is configured such that, when the biotelemetry device (100) is placed in the biological medium (110), it can be impedance-mismatched relative to the radiofrequency circuit (102) so as to generate a reflected electrical signal (RS) by reflecting a fraction of the incident electrical signal at the same time that the radio antenna is transmitting the electromagnetic wave (EMS).

Abstract: The present description concerns a memory device (200) including a non-volatile memory circuit (101); a buffer memory circuit (203) comprising a volatile memory circuit (221); an input-output circuit (105); a first data link (104) coupling the non-volatile memory circuit (101) to the buffer memory circuit (203); a second data link (106) coupling the buffer memory circuit (203) to the input-output circuit (105); and a control circuit (225), wherein the buffer memory circuit (203) is adapted to implementing calculations having as operands data stored in the volatile memory circuit (221).

Abstract: A method for interconnecting components of an electronic system includes depositing a sintering solution onto a first component to form an interconnection layer, the sintering solution comprising a solvent, metal nanoparticles dispersed in the solvent, and a stabilizing agent adsorbed onto the nanoparticles. More than 95.0%, preferably more than 99.0% of the mass of the nanoparticles include a metal selected from silver, gold, copper and alloys thereof and have a polyhedral shape with an aspect ratio greater than 0.8. The method also includes eliminating, at least partially, the solvent from the layer to form an ordered agglomerate in which the nanoparticles are regularly disposed in three axes, the stabilizing agent binding them together and maintaining at least a portion of the nanoparticles at a distance from each other, debinding and sintering the layer, and depositing a second component in contact with the layer before or during debinding or sintering.

Abstract: The invention concerns a method for processing energy spectra of radiation transmitted by an object irradiated by an ionising radiation source, in particular X-ray radiation, for medical imaging or non-destructive testing applications. The method uses a detector comprising a plurality of pixels, each pixel being capable of acquiring a spectrum of the radiation transmitted by the object. The method makes it possible, based on a plurality of detected spectra, to estimate a spectrum, referred to as the scattering spectrum, representative of radiation scattered by the object. The estimation involves taking into account a spatial model of the scattering spectrum. Each acquired spectrum is corrected taking into account the estimated scattering spectrum. The invention makes it possible to reduce the influence of the scattering, by the object, of the spectrum emitted by the source.

Abstract: Memory devices such as phase change memory (PCM) devices utilizing Ovonic Threshold Switching (OTS) selectors may be used to fill the gap between dynamic random-access memory (DRAM) and mass storage and may be incorporated in high-end microcontrollers. Since the programming efficiency and reading phase efficiency of such devices is directly linked to the leakage current of the OTS selector as well as sneak-path management, a sense amplifier disclosed herein generates an auto-reference that takes into account the leakage currents of unselected cells and includes a regulation loop to compensate for voltage drop due to read current sensing. This auto-referenced sense amplifier, built utilizing the principle of charge-sharing, may be designed on a 28 nm fully depleted silicon-on-insulator (FDSOI) technology, provides robust performance for a wide range of sneak-path currents and consequently for a large range of memory array sizes, and is therefore suitable for use in embedded memory in high-end microcontroller.

Abstract: The present invention relates to methods and composition for use in the treatment of retinal degeneration, in particular retinal degeneration due to retinal pigment epithelium dysfunction.

Abstract: The invention relates to the identification of a highly stable single domain antibody scaffold (hs2dAb) and its use in generating synthetic single domain antibody library (hs2dAb-L1). The invention also relates to antigen-binding proteins comprising said stable single domain antibody scaffold and their uses, in particular as therapeutics.

Abstract: The invention relates to a composition comprising a blend of fluorinated electroactive polymers and having a dielectric permittivity that exhibits greater stability over the operating temperature range with respect to each polymer employed on its own. The invention also relates to formulations and films produced on the basis of said composition. The invention also relates to a field-effect transistor, at least part of the dielectric layer of which is composed of a blend of fluorinated electroactive polymers.

Abstract: A device for forcibly inserting a surgical implant into a receiving bone (4), by impaction, comprising an impactor (10) which exerts an impact force on the implant and is associated with at least one sensor (12). The sensor (12) measures the deformation of the impactor (10), and provides a measurement signal representing the temporal variation of the deformation during an impact. The sensor (12) is connected to a processing unit (30) configured to calculate, on the basis of the temporal variation of the deformation of the impactor (10) during the impact, an indicator representative of the level of contact between the implant and the receiving bone (4).

Abstract: A device for assessing the solidity of a material comprising an ancillary tool (2) having an end (2B) in the form of a point or blade, an impactor (4) for striking the ancillary tool (2), a sensor (12) and a processing unit (30). The ancillary tool (2) is placed between a material (8) and the impactor (4) and transmits the impact force generated by the impactor (4) to the material (8). The sensor (12) is capable of measuring a quantity from among the impact force and the deformation of the impactor, and of supplying a measurement signal. The processing unit (30) is suitable for calculating, from the measurement signal, an indicator representative of the solidity of the material (8). The indicator corresponds to the duration of a time window between the first peak (P1) of maximum amplitude of the measurement signal and the second peak of maximum amplitude (P2).

Abstract: A method for coating fibers, includes desizing sized short fibers having an average length less than or equal to 5 mm, the short fibers being made of ceramic material or carbon, sieving the desized short fibers in order to separate them from any agglomerates of sized short fibers still present, introducing the desized and sieved short fibers into a reactor, and coating the short fibers in the reactor by chemical vapor deposition in a fluidized bed.

Abstract: The invention is directed to a recombinant Adeno-Associated Virus (rAAV) vector particle having at least one primary amino group contained in the capsid proteins, chemically coupled with at least one ligand L, wherein coupling of said ligand L is implemented through a bond comprising a —CSNH— bond and an optionally substituted aromatic moiety. The present invention further relates to a method for chemically coupling an Adeno-Associated Virus (AAV) vector particle with at least one ligand L and to a Recombinant Adeno-Associated Virus (rAAV) vector particle obtained by said method as well as a pharmaceutical composition comprising it and their corresponding medical use.