Patents Assigned to Centre National de la Recherche Scientique - CNRS
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Publication number: 20190001252Abstract: A subject of the present invention is the use of a compound having the general formula (I): (I) wherein V, W, X4, X5, X6, X7, X?4, X?5, X?6, X?7, Y, Y?, R3, R?3, R4 and R?4 are as defined in any one of claims 1 to 11, for the detection, capture and/or separation of polluting gases, in particular those selected from the group comprising carbon dioxide, methane, sulfur dioxide, nitrogen oxides, carbon monoxide, linear hydrocarbons, linear mono-olefins and their mixtures, and preferably carbon dioxide. Another subject of the invention is a compound of formula (I) wherein V, W, X4, X5, X6, X7, X?4, X?5, X?6, X?7, Y, Y?, R3, R?3, R4 and R?4 are as defined in any one of claims 12 to 21.Type: ApplicationFiled: December 23, 2016Publication date: January 3, 2019Applicants: Centre National de la Recherche Scientique -CNRS-, Université d'Aix-MarseilleInventors: Jean-Manuel Raimundo, Vinicius Demétrio da Silva, Philip Leslie Llewellyn, Julien Rodriguez, Olivier Yves Claude Siri
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Patent number: 9611320Abstract: The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. The present disclosure is further directed to methods comprising detection of progastrin, including methods of diagnosing colorectal cancer and methods of monitoring efficacy of anti-cancer therapy in subjects suffering from colorectal cancer.Type: GrantFiled: October 15, 2010Date of Patent: April 4, 2017Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (CNRS), LES LABORATOIRES SERVIERInventors: Julie Pannequin, Laure Boudier, Dominique Joubert, Frédéric Hollande
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Patent number: 9487582Abstract: The present disclosure is directed to methods of treating pancreatic cancer in subject using cancer with antibodies that specifically bind to progastrin.Type: GrantFiled: January 4, 2011Date of Patent: November 8, 2016Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (CNRS), LES LABORATORIES SERVIERInventors: Leïla Houhou, Dominique Joubert, Frédéric Hollande
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Publication number: 20150184122Abstract: A guiding device in which cells are confined between a support surface and a textured surface of a substrate, said textured surface having an anisotropic three-dimensional structure having a repeating pattern that repeats according to a repeat axis, said repeating pattern having a succession of guide spaces adjacent to one another according to the repeat axis, each of said guide spaces being capable of receiving at least one portion of one of the cells and being oriented according to a direction of anisotropy to guide a movement of the cells in the direction of anisotropy.Type: ApplicationFiled: September 17, 2012Publication date: July 2, 2015Applicants: Institut Curie, Centre National de la Recherche Scientique - CNRS, Societe de Developpement et de Recherche IndustrielleInventors: Maël Le Berre, Matthieu Piel, Yanjun Liu
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Publication number: 20150153471Abstract: An electromagnetic system for exploring the seabed in a marine environment includes a current injection module with two electrodes spaced apart from one another, said injection electrodes being capable of injecting a current at a predetermined voltage into the marine environment close to the seabed, said injection electrodes having a contact surface with the marine environment. The system includes a data acquisition module with at least two measuring sensors for measuring electrical or magnetic data at at least two points of the marine environment close to the seabed, and a power supply module for supplying power to the current injection module. Each electrode includes one or more separate conductive elements that are electrically connected to each other and arranged in such a way as to form a conductive network or a multilayer conductive assembly having a large contact surface with the marine environment.Type: ApplicationFiled: January 9, 2013Publication date: June 4, 2015Applicants: UNIVERSITE DE BRETAGNE OCCIDENTALE - UBO, CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE - CNRSInventors: Jean-François D'eu, Pascal Tarits, Fabien Gaspari
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Publication number: 20140228460Abstract: An interconnected microcellular material, a method for preparing said material using low-value waste from the paper industry, such as industrial lignin, and the use thereof for the production of items such as catalysts, filters or absorbent elements.Type: ApplicationFiled: September 27, 2012Publication date: August 14, 2014Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (CNRS), UNIVERSITE DE BORDEAUXInventors: Herve Deleuze, Claire Forgacz, Marc Birot
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Patent number: 6812017Abstract: DNA and peptide sequences encoding a novel mammalian secreted group IIF phospholipase A2 wherein said enzyme is Ca2+-dependent, maximally active at pH 7-8, and hydrolyzes phosphatidylglycerol versus phosphatidylcholine with a 15-fold preference and more particularly, a novel human group IIF phospholipase A2. The invention also concerns the use of this enzyme in methods for screening various chemical compounds.Type: GrantFiled: October 11, 2001Date of Patent: November 2, 2004Assignee: Centre National de la Recherche Scientique - CNRSInventors: Michel Lazdunski, Gérard Lambeau, Emmanuel Valentin