Abstract: The invention relates to a material which can be implanted in living tissue, in particular bony tissue, and having a rate of biodegradation adapted to the rate at which the tissue is regenerated; this material may comprise an active substance in order to achieve a therapeutic effect of prolonged duration. This material comprises (a) a calcium phosphate with apatitic or triclinic structure comprising HPO.sub.4 and PO.sub.4 groups, (b) a biodegradable oside or polyoside, in particular dextran, (c) if required, an active substance comprising amine groups such as netilmicin and/or gentamicin in sulphate form. The implantable material according to the invention may be produced without heat by compacting its various constituents in the powdery state.