Abstract: Disclosed is a scaffolding protein having SEQ ID NO: 1, derived from a conotoxin, which does not have amino acid residues associated with the toxic activity of the conotoxin and which can be used to generate chimeral proteins having 19-47 amino acids, fragments of a CDR3 of a vNAR with affinity for a specific antigen being inserted between amino acids 11 and 12 thereof.
Type:
Application
Filed:
November 19, 2021
Publication date:
November 23, 2023
Applicant:
CENTRO DE INVESTIGACIÓN CIENTÍFICA Y DE EDUCACIÓN SUPERIOR DE ENSENADA, BAJA CALIFORNIA (CICESE)
Abstract: A method to increase the biomass production and fatty acids in the alga Chlorella vulgaris Beyerinck and obtain a lipid rich biomass type C:16 (palmitic), C18:1n-9 (oleic), C18:2n-6t (linoleidic) and C18:3n-3 (alpha-linolenic), which uses low irradiance from a dichromatic light source.
Type:
Application
Filed:
December 13, 2019
Publication date:
February 24, 2022
Applicant:
CENTRO DE INVESTIGACIÓN CIENTÍFICA Y DE EDUCACIÓN SUPERIOR DE ENSENADA, BAJA CALIFORNIA (CICESE)
Abstract: The present invention relates to a novel vNAR protein of SEQ ID No: 1 capable of inhibiting the activity of VEGF in carnivorous mammals of the Canis and Felis genera, thereby inhibiting solid tumors growth of both genres.
Type:
Application
Filed:
April 20, 2018
Publication date:
May 28, 2020
Applicants:
CENTRO DE INVESTIGACIÓN CIENTÍFICA Y DE EDUCACIÓN SUPERIOR DE ENSENADA, BAJA CALIFORNIA, LABORATORIOS SILANES, S.A. DE C.V., TERACLÓN IDF, NOVA PROTEINS S.A. DE C.V.
Inventors:
Alexei Fedorovish LICEA NAVARRO, Dalia Vanessa MILLÁN GÓMEZ, Liliana Noemi SÁNCHEZ CAMPOS, Carolina ELOSUA PORTUGAL, Jorge Fernando PANIAGUA SOLÍS, Salvador DUEÑAS ESPINOZA
Abstract: A protocol for the cryopreservation of high viscosity biological samples, preferably of spermatic samples of crustaceans or insects, that enables maintaining intact the physical properties of the original sample preserving the viability of the sperm packet.
Type:
Application
Filed:
September 18, 2017
Publication date:
July 18, 2019
Applicant:
CENTRO DE INVESTIGACIÓN CIENTÍFICA Y DE EDUCACIÓN SUPERIOR DE ENSENADA, BAJA CALIFORNIA (CICESE)
Inventors:
Karina MORALES UENO, Carmen Guadalupe PANIAGUA CHÁVEZ
Abstract: The present invention relates to processes for obtaining metal oxides by irradiation of low energy laser pulses of metal layers, wherein said metals can be formed as simple metals, alloys, or multilayers. The present invention performs the oxidation of a thin metal film deposited on a substrate; e.g., glass (SiO2) or silicon (Si) by a laser-irradiation time of a few nanoseconds to femtoseconds at high repetition rate, time necessary to achieve a stoichiometry and a well-defined microscopic structure. Through the processes of the invention, it is possible to obtain complex structures and metal oxides at room temperature in a very short time and with very low energy consumption.
Type:
Application
Filed:
December 21, 2015
Publication date:
May 19, 2016
Applicant:
Centro de Investigación Cientifica y de Educación Superior de Ensenada, Baja California
Inventors:
Santiago CAMACHO LÓPEZ, Marco Antonio CAMACHO LÓPEZ
Abstract: The invention relates to an isolated or recombinant protein from the shark Heterodontus francisci, which has bovine-erythrocyte-recognition activity and which can bind to sequences of antigens and/or proteins that are characteristic of infectious diseases. Once the aforementioned protein is bound to specific antigens of infectious diseases, it can haemagglutinate upon recognizing the bovine erythrocytes and antibodies characteristic of said diseases, which are present in the active state in biological samples such as whole blood, plasma or serum of bovine origin. The invention also relates to methods for protecting the detection of antibodies characteristic of infectious diseases, using the purified periplasmic extract or fusion protein, optionally purifying the recombinant protein.
Type:
Grant
Filed:
February 21, 2013
Date of Patent:
March 15, 2016
Assignee:
Centro de Investigacion Cientifica Y de Educacion Superior de Ensenada, Baja California (CICESE)
Inventors:
Alexei Fedorovish Licea Navarro, Jose Felix Olivares Quintero, Ana Paola Gutierrez Ordonez