Patents Assigned to Centro de Investigacion y de Estudios Avanzados Del Instituto Politecnico Nacional
-
Publication number: 20210324402Abstract: System, including methods and compositions, for making and using transgenic plants and/or transgenic fungi that metabolize phosphite as a source of phosphorus for supporting growth.Type: ApplicationFiled: November 30, 2020Publication date: October 21, 2021Applicant: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV)Inventors: Luis R. Herrera-Estrella, Damar L. López-Arredondo, Alfredo Heriberto Herrera-Estrella
-
Patent number: 11121760Abstract: The invention described herein presents a system and method to overcome the distortions and affectations introduced by the highly variant channels of one or several antennas both in the transmitter and in the receiver. Unlike any existing invention that operates under the same conditions, this device uses a completely new reception technique based on the concept of virtual trajectories in which iterative calculations or solution of linear systems in operating time are not required, thus saving a considerable amount of operations. The receiver of this device manages to convert the fast variations of the channel into virtual antennas, thus achieving a considerable increase in the signal to noise-interference ratio. The resulting performance in terms of noise immunity is much better than any technique found so far and also requires a much smaller amount of calculations in the receiver.Type: GrantFiled: April 6, 2017Date of Patent: September 14, 2021Assignee: CENTRO DE INVESTIGACION Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITECNICO NACIONALInventors: Fernando Peña Campos, Ramón Parra Michel, Valeri Kontorovich Mazover
-
Patent number: 10851386Abstract: System, including methods and compositions, for making and using transgenic plants capable of metabolizing phosphite to reduce competition from weeds. The plants may be transgenically modified to express a phosphite dehydrogenase enzyme capable of catalyzing oxidation of phosphite to phosphate and grown in the presence of sufficient phosphite to selectively promote growth of the plant relative to weeds near the plant.Type: GrantFiled: July 27, 2012Date of Patent: December 1, 2020Assignee: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV)Inventors: Luis Rafael Herrera-Estrella, Damar Lisbeth López-Arredondo
-
Publication number: 20200067617Abstract: Currently the channel emulation is carried out by means of stationary channel realizations in order to perform the tests and validation of the new data communication schemes. However, the channel models available in the state of the art have only been efficiently used to perform channel simulation using software, leaving its efficient implementation in Hardware still unsolved. The present development details a method and apparatus for performing the channel emulation of time selective scenarios with arbitrary dispersion (channels with both isotropic and non-isotropic arrival angle distributions or channels with asymmetric and non-asymmetric power spectral densities). Likewise, the present development allows generating arbitrarily long channel realizations for channels whose statistics are non-stationary, allowing to emulate real channels.Type: ApplicationFiled: April 5, 2017Publication date: February 27, 2020Applicant: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico NacionalInventor: Ramón PARRA MICHEL
-
Publication number: 20200036428Abstract: The invention described herein presents a system and method to overcome the distortions and affectations introduced by the highly variant channels of one or several antennas both in the transmitter and in the receiver. Unlike any existing invention that operates under the same conditions, this device uses a completely new reception technique based on the concept of virtual trajectories in which iterative calculations or solution of linear systems in operating time are not required, thus saving a considerable amount of operations. The receiver of this device manages to convert the fast variations of the channel into virtual antennas, thus achieving a considerable increase in the signal to noise-interference ratio. The resulting performance in terms of noise immunity is much better than any technique found so far and also requires a much smaller amount of calculations in the receiver.Type: ApplicationFiled: April 6, 2017Publication date: January 30, 2020Applicant: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico NacionalInventors: Fernando PEÑA CAMPOS, Ramón PARRA MICHEL, Javier VAZQUEZ, CASTILLO
-
Patent number: 10414796Abstract: The present invention describes a new peptide aldehyde produced naturally by Streptomyces lividans 66, which we have called livipeptin. Using genome mining of natural products, we predicted that SLI0883-5 genes encode an unprecedented biosynthetic system, unusually small (4.6 Kbp), which produces an acylated peptide aldehyde. Because of the chemical characteristics of the predicted compound, we postulated its anti-proteolytic activity, which we confirmed by identifying and purifying this compound through metabolic profiles of HPLC and MS of the mutated strain lacking these three genes and the wild strain. To this objective, we identified the conditions wherein these genes are strongly expressed. The livipeptin was purified and its inhibitory activity on the proteolytic activity of selected proteases was demonstrated in vitro. The design of an expression cassette for its heterologous expression is also described plus its use for heterologous protein production.Type: GrantFiled: December 14, 2015Date of Patent: September 17, 2019Assignee: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico NacionalInventors: Pablo Cruz Morales, Francisco Barona Gómez, Hilda Eréndira Ramos Aboites
-
Publication number: 20180265545Abstract: The present invention describes a new peptide aldehyde produced naturally by Streptomyces lividans 66, which we have called livipeptin. Using genome mining of natural products, we predicted that SLl0883-5 genes encode an unprecedented biosynthetic system, unusually small (4.6 Kbp), which produces an acylated peptide aldehyde. Because of the chemical characteristics of the predicted compound, we postulated its anti-proteolytic activity, which we confirmed by identifying and purifying this compound through metabolic profiles of HPLC and MS of the mutated strain lacking these three genes and the wild strain. To this objective, we identified the conditions wherein these genes are strongly expressed. The livipeptin was purified and its inhibitory activity on the proteolytic activity of selected proteases was demonstrated in vitro. The design of an expression cassette for its heterologous expression is also described plus its use for heterologous protein production.Type: ApplicationFiled: December 14, 2015Publication date: September 20, 2018Applicant: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico NacionalInventors: Pablo CRUZ MORALES, Francisco BARONA GÓMEZ, Hilda Eréndira RAMOS ABOITES
-
Patent number: 9362100Abstract: The present invention relates to a non-thermal plasma jet device as spatial ionization source for ambient mass spectrometry of the type which allows a free adjustment of the geometry of the plasma beam, wherein the device comprises a double dielectric barrier probe of non-thermal plasma or NTP probe, which generates a non-thermal plasma jet; a high voltage and high frequency transformer circuit that connects an outer electrode through which it is possible to perform a discharge for the ionization of a gas which produces plasma, and wherein said plasma generator circuit is in turn connected to a source of AC power; an inner electrode which is grounded and allows to perform the discharge for the production of plasma; a storage tank of a gas serving as discharge gas; a test sample on which the non-thermal plasma jet is applied; and a ion transfer adapter to direct the ions produced by the device from the vacuum-free sample into a mass analyzer.Type: GrantFiled: October 7, 2013Date of Patent: June 7, 2016Assignee: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico NacionalInventors: Sandra Martínez Jarquín, Robert Winkler
-
Publication number: 20150335764Abstract: The present invention pertains to the field of genomics and nanotechnology, specifically to the in vivo gene expression technologies and their application in gene therapy. It consists of the performance of the NTS-polyplex nanocomplex, which can carry nucleic acids to the neurons, involving neurotrophic therapy to treat neurodegenerative diseases. In particular, the present invention addresses the treatment of Parkinson's disease by the regulated expression of the BDNF neurotrophin.Type: ApplicationFiled: September 4, 2013Publication date: November 26, 2015Applicant: CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITÉCNICO NACIONALInventor: Daniel Martinez Fong
-
Publication number: 20140099796Abstract: A method for porogen removal of porous SiOCH film is provided, as well as devices obtained thereof. The devices and associated methods are in the field of advanced semiconductor interconnect technology, and more in particular in the development of dielectric films with low-k value.Type: ApplicationFiled: October 3, 2013Publication date: April 10, 2014Applicants: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, IMECInventors: Patrick Verdonck, Srinivas Godavarthi, Yasuhiro Matsumoto
-
Publication number: 20140088196Abstract: System, including methods compositions, and kits, for controlling the growth of fungi and other pathogens in plants using at least one alkamide, which may function by increasing or eliciting natural defense mechanisms of the plants against such pathogens.Type: ApplicationFiled: September 16, 2013Publication date: March 27, 2014Applicant: Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional (CINVESTAV)Inventors: José López-Bucio, Jorge Molina-Torres, Luis Rafael Herrera-Estrella
-
Patent number: 8681937Abstract: The present invention is related to an apparatus and method to carry out image-guided radiotherapy or radiosurgical treatments using Kilovoltage X-ray beams; one of the problems with the clinical application of this treatment consists in the absorbed dosage imparted unto a point within the subject to be irradiated depends on the local concentration of the contrast agent at that point, and the lack of properly quantifying the presence of the contrast agent at each point of the tumor or malformation to be irradiated results in a significant decrease in the quality of the treatment; the method and apparatus of the present invention resolve this and other problems.Type: GrantFiled: July 28, 2011Date of Patent: March 25, 2014Assignee: Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico NacionalInventor: Hector Mauricio Garnica Garza
-
Publication number: 20140069008Abstract: A plant cultivation system, including methods, apparatus, plants, and compositions, for utilizing phosphite as a nutrient to support growth of a transgenic plant and as a control agent for unwanted organisms, such as weeds and/or algae, among others. In an exemplary method, an effective amount of phosphite is applied to a substrate, and/or to foliage above the substrate, to enhance growth of a transgenic plant and/or to act as a weed-control agent that kills weeds and/or directly suppresses growth of weeds near the transgenic plant. In another exemplary method, soil is tested for a content of phosphate, and an effective amount of phosphite for supporting growth of a transgenic plant and controlling weeds is selected and applied based on the content of phosphate. In yet another exemplary method, phosphite is used to control algae in a hydroponic system.Type: ApplicationFiled: December 7, 2011Publication date: March 13, 2014Applicant: Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional (CINVESTAV)Inventors: Luis Rafael Herrera-Estrella, Damar Lizbeth López-Arredondo
-
Patent number: 8613545Abstract: The present invention describes a scan adiabatic resistive calorimeter (SARC) 1 with ohm heating of the sample 20, which measures the heating enthalpy and is formed of an inner cylinder 11 and a couple of pistons 15 and 16, thus forming said elements a cylindrical chamber hermetically closed 10, which avoids that during its operation can be material losses by leaks. Pistons 15 and 16 have, in one of their ends an electrode 31 and 36 respectively and they pass the electrical heating flow through the sample 20. In reference to this electric flow, the applied power is calculated and therefore, the supplied heat to the sample 20, which is equal to the specific enthalpy. To assure that the whole of the electric flow is conducted through the sample 20, the inner cylinder 11 is electrically isolated.Type: GrantFiled: November 7, 2008Date of Patent: December 24, 2013Assignee: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico NacionalInventors: Alberto Herrera Gómez, José Martín Yáñez Limón, Guadalupe Barreiro Rodríguez, Carlos Alberto Contreras Servín
-
Publication number: 20130067975Abstract: System, including methods and compositions, for making and using transgenic plants capable of metabolizing phosphite to reduce competition from weeds.Type: ApplicationFiled: July 27, 2012Publication date: March 21, 2013Applicant: Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV)Inventors: Luis Rafael Herrera-Estrella, Damar Lisbeth López-Arredondo, Alfredo Heriberto Herrera-Estrella
-
Patent number: 8383129Abstract: The present invention refers to the use of rotavirus proteins VP4, VP8 and their derived fusion proteins and peptides, for enhancing the delivery of pharmaceutical agents through the paracellular pathway. These rotavirus proteins and derived peptides may additionally be employed to reduce unwanted cellular adhesion that can occur between cancerous cells, or between normal cells as a result of surgery, injury, chemotherapy, disease, inflammation or other pathological conditions.Type: GrantFiled: January 10, 2003Date of Patent: February 26, 2013Assignee: Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico NacionalInventors: Lorenza Gonzalez-Mariscal, Porfirio Nava-Dominguez
-
Publication number: 20120295303Abstract: System, including methods and compositions, for making and using photosynthetic organisms and cells that are adapted transgenically to metabolize phosphite as a source of phosphorus for supporting growth.Type: ApplicationFiled: July 27, 2012Publication date: November 22, 2012Applicant: Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional (CINVESTAV)Inventors: Luis Rafael Herrera-Estrella, Damar Lizbeth López-Arredondo, Alfredo Heriberto Herrera-Estrella
-
Publication number: 20120285210Abstract: System, including methods and compositions, for making and using fungi that are adapted transgenically to metabolize phosphite as a source of phosphorus for supporting growth.Type: ApplicationFiled: July 27, 2012Publication date: November 15, 2012Applicant: Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional (CINVESTAV)Inventors: Luis Rafael Herrera-Estrella, Damar Lizbeth López-Arredondo, Alfredo Heriberto Herrera-Estrella
-
Publication number: 20100296544Abstract: The present invention describes a scan adiabatic resistive calorimeter (SARC) 1 with ohm heating of the sample 20, which measures the heating enthalpy and is formed of an inner cylinder 11 and a couple of pistons 15 and 16, thus forming said elements a cylindrical chamber hermetically closed 10, which avoids that during its operation can be material losses by leaks. Pistons 15 and 16 have, in one of their ends an electrode 31 and 36 respectively and they pass the electrical heating flow through the sample 20. In reference to this electric flow, the applied power is calculated and therefore, the supplied heat to the sample 20, which is equal to the specific enthalpy. To assure that the whole of the electric flow is conducted through the sample 20, the inner cylinder 11 is electrically isolated.Type: ApplicationFiled: November 7, 2008Publication date: November 25, 2010Applicant: CENTRO DE INVESTIGACION Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITECNICO NACIONALInventors: Alberto Herrera Gomez, Jose Martin Yanez Limon, Guadalupe Barreiro Rodriguez, Carlos Alberto Contreras Servin
-
Patent number: 5660977Abstract: An improved method and fermentor for aerobic production of microbial cells and/or cell metabolites, having at least one ascending flow chambers and at least one descending flow chamber. The fermentor is especially useful in conducting high cell density fermentation processes which involves the controlled addition of an antifoam agent, for maintaining a predetermined and relatively high gas holdup within the fermentor or by release of the constituents of the microbial cells into the fermentor.Type: GrantFiled: September 18, 1995Date of Patent: August 26, 1997Assignee: Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico NacionalInventors: Luis Bernardo Flores-Cotera, Sergio Garcia-Salas