Patents Assigned to Centro de Investigacion y Estudios Avanzados del Instituto Politecnico Nacional
  • Process for the long-term surviving culture of hepatocytes
    Patent number: 5030105
    Abstract: A process is disclosed for the long term surviving culture of hepatocytes maintaining their morphological and functional characteristics for long-term-periods, suitable to assest the acute and chronic hepatotoxicity of drugs, chemicals and environmental pollutants. The long term surviving culture of hepatocytes is carried out in a culture media containing fibroblast cells or fibroblast cell products treated to prevent cell multiplication and inoculated under controlled density.
    Type: Grant
    Filed: November 15, 1989
    Date of Patent: July 9, 1991
    Assignee: Centro de Investigacion y Estudios Avanzados del Instituto Politecnico Nacional
    Inventors: Walid Kuri-Harcuch, Tomas Mendoza-Figueroa