Abstract: Monoclonal antibodies directed to ceramide that inhibit apoptosis are disclosed. Humanized and scFv versions of the antibodies are also disclosed. Methods for prevention or treatment of apoptosis in a subject by administration of the anti-ceramide antibodies are disclosed.
Type:
Grant
Filed:
September 11, 2019
Date of Patent:
September 20, 2022
Assignees:
MEMORIAL SLOAN KETTERING CANCER CENTER, CERAMIDE THERAPEUTICS
Abstract: Monoclonal antibodies directed to ceramide that inhibit apoptosis are disclosed. Humanized and scFv versions of the antibodies are also disclosed. Methods for prevention or treatment of apoptosis in a subject by administration of the anti-ceramide antibodies are disclosed.
Type:
Application
Filed:
September 11, 2019
Publication date:
December 26, 2019
Applicants:
MEMORIAL SLOAN KETTERING CANCER CENTER, CERAMIDE THERAPEUTICS
Abstract: Monoclonal antibodies directed to ceramide that inhibit apoptosis are disclosed. Humanized and scFv versions of the antibodies are also disclosed. Methods for prevention or treatment of apoptosis in a subject by administration of the anti-ceramide antibodies are disclosed.
Type:
Grant
Filed:
August 7, 2015
Date of Patent:
October 22, 2019
Assignees:
Memorial Sloan Kettering Cancer Center, Ceramide Therapeutics