Patents Assigned to Cerbios Pharma S.A.
  • Process for the preparation of 9, 10-secocholesta-5,7,10 (19)-trienes
    Patent number: 5698714
    Abstract: The invention recites a process for preparing 9,10-secocholesta-5,7,10(19)-trienes of formula (I) ##STR1## where R.sup.1 is hydrogen or a hydroxy-protecting group and R.sup.2 and R.sup.3 are independently hydrogen or OR.sup.1. The compounds are prepared from epoxides of the following formulas ##STR2## by reaction with a low-valent metal reagent formed by reducing a metal halide, M(z)X.sub.z, preferably WCl.sub.6.
    Type: Grant
    Filed: July 11, 1996
    Date of Patent: December 16, 1997
    Assignee: Cerbios Pharma S.A.
    Inventors: Christof Schickli, Mathias Jud, Fabrizio Marazza