Patents Assigned to Cercacor Laboratories, Inc.
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Patent number: 8570503Abstract: A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a heat sink that can direct heat away from the light source.Type: GrantFiled: June 15, 2012Date of Patent: October 29, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Hung Vo, Marcelo Lamego, Sean Merritt, Cristiano Dalvi, Johannes Bruinsma, Jeroen Poeze, Ferdyan Lesmana, Greg Olsen, Massi Joe E. Kiani
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Patent number: 8560032Abstract: Embodiments of the present disclosure include a handheld multi-parameter patient monitor capable of determining multiple physiological parameters from the output of a light sensitive detector capable of detecting light attenuated by body tissue. For example, in an embodiment, the monitor is capable of advantageously and accurately displaying one or more of pulse rate, plethysmograph data, perfusion quality, signal confidence, and values of blood constituents in body tissue, including for example, arterial carbon monoxide saturation (“HbCO”), methemoglobin saturation (“HbMet”), total hemoglobin (“Hbt”), arterial oxygen saturation (“SpO2”), fractional arterial oxygen saturation (“SpaO2”), or the like. The monitor can determine which a plurality of light emitting sources and which of a plurality of parameters to measure based on the signal quality and resources available.Type: GrantFiled: May 22, 2012Date of Patent: October 15, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Ammar Al-Ali, Joe E. Kiani, Mohamed Diab, Roger Wu, Rick Fishel
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Patent number: 8548550Abstract: An embodiment of the present disclosure provides a noninvasive optical sensor or probe including disposable and reusable components. The assembly of the disposable and reusable components is straightforward, along with the disassembly thereof. During application to a measurement site, the assembled sensor is advantageously secured together while the componentry is advantageously properly positioned.Type: GrantFiled: July 31, 2012Date of Patent: October 1, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Ammar Al-Ali, Yassir Abdul-Hafiz
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Patent number: 8515509Abstract: The present disclosure relates to an emitter that is suitable for a noninvasive blood constituent sensor. The emitter is configured as a point optical source that comprises a plurality of LEDs that emit a sequence of pulses of optical radiation across a spectrum of wavelengths. In some embodiments, the plurality of sets of optical sources may each comprise at least one top-emitting LED and at least one super luminescent LED. In some embodiments, the emitter comprises optical sources that transmit optical radiation in the infrared or near-infrared wavelengths suitable for detecting glucose. In order to achieve the desired SNR for detecting analytes like glucose, the emitter may be driven using a progression from low power to higher power. In addition, the emitter may have its duty cycle modified to achieve a desired SNR.Type: GrantFiled: August 3, 2009Date of Patent: August 20, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Johannes Bruinsma, Marcelo Lamego, Sean Merritt, Cristiano Dalvi, Hung Vo, Jeroen Poeze, Ferdyan Lesmana, Massi Joe E. Kiani
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Publication number: 20130211214Abstract: A patient monitoring system can display one or more configurable health monitors on a configurable user interface. The health indicators are configured to display a physiological signal from a patient. The patient monitoring system can calculate ranges of values for the health indicator that correspond to a status of the patient. The health indicators can display different outputs based on the value of the physiological signal.Type: ApplicationFiled: February 8, 2013Publication date: August 15, 2013Applicant: CERCACOR LABORATORIES, INC.Inventor: Cercacor Laboratories, Inc.
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Patent number: 8509867Abstract: This invention provides devices, compositions and methods for determining the concentration of one or more metabolites or analytes in a biological sample, including cells, tissues, organs, organisms, and biological fluids. In particular, this invention provides materials, apparatuses, and methods for several non-invasive techniques for the determination of in vivo blood glucose concentration levels based upon the in vivo measurement of one or more biologically active molecules found in skin.Type: GrantFiled: February 7, 2006Date of Patent: August 13, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Jerome J. Workman, Christopher R. Lambert, Robert L. Coleman
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Publication number: 20130178749Abstract: A tissue profile wellness monitor measures a physiological parameter, generates a tissue profile, defines limits and indicates when the tissue profile exceeds the defined limits. The physiological parameter is responsive to multiple wavelengths of optical radiation after attenuation by constituents of pulsatile blood flowing within a tissue site. The tissue profile is responsive to the physiological parameter. The limits are defined for at least a portion of the tissue profile.Type: ApplicationFiled: February 11, 2013Publication date: July 11, 2013Applicant: CERCACOR LABORATORIES, INC.Inventor: CERCACOR LABORATORIES, INC.
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Patent number: 8483787Abstract: A physiological sensor includes an electrical grid to activate one or more light emitters by addressing at least one row conductor and at least one column conductor. Each light emitter includes a positive terminal and a negative terminal. The physiological sensor includes a first light emitter and a second light emitter. A first contact is communicatively coupled with the positive terminal of the first light emitter, the negative terminal of the second light emitter, a first row conductor, and a first column conductor. A second contact is communicatively coupled with the negative terminal of the first light emitter, the positive terminal of the second light emitter, a second row conductor, and a second column conductor. The first light emitter is activated by addressing the first row conductor and the second column conductor. The second light emitter is activated by addressing the second row conductor and the first column conductor.Type: GrantFiled: October 31, 2011Date of Patent: July 9, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Ammar Al-Ali, Robert Smith, David Dalke, Mohamed Diab, Marcelo Lamego
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Publication number: 20130172701Abstract: A physiological sensor has light emitting sources, each activated by addressing at least one row and at least one column of an electrical grid. The light emitting sources are capable of transmitting light of multiple wavelengths and a detector is responsive to the transmitted light after attenuation by body tissue.Type: ApplicationFiled: February 25, 2013Publication date: July 4, 2013Applicant: CERCACOR LABORATORIES, INC.Inventor: CERCACOR LABORATORIES, INC.
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Patent number: 8471713Abstract: A system is disclosed for detecting and calculating the level of ambient and/or environmental noise, such as electromagnetic interference generated by electric power lines, ambient lights, light dimmers, television or computer displays, power supplies or transformers, and medical equipment. In some embodiments, the system performs frequency analysis on the interference signal detected by light photodetectors and determines the power of the interference signal concentrated in the analyzed frequency bands. The worst-case interference level can be determined by selecting the maximum from the computed power values. In some embodiments, the determined interference signal power can be compared with the noise tolerance of a patient monitoring system configured to reliably and non-invasively detect physiological parameters of a user. The results of the comparison can be presented to the user audio-visually. In some embodiments, the system can be used to perform spot check measurements of electromagnetic interference.Type: GrantFiled: July 22, 2010Date of Patent: June 25, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Jeroen Poeze, Jesse Chen, Mathew Paul, Marcelo Lamego, Massi Joe E. Kiani
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Patent number: 8473020Abstract: A sensor cover according to embodiments of the disclosure is capable of being used with a non-invasive physiological sensor, such as a pulse oximetry sensor. Certain embodiments of the sensor cover reduce or eliminate false readings from the sensor when the sensor is not in use, for example, by blocking a light detecting component of a pulse oximeter sensor when the pulse oximeter sensor is active but not in use. Further, embodiments of the sensor cover can prevent damage to the sensor. Additionally, embodiments of the sensor cover prevent contamination of the sensor.Type: GrantFiled: July 27, 2010Date of Patent: June 25, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Abraham Mazda Kiani, Massi Joe E. Kiani
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Patent number: 8466286Abstract: Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.Type: GrantFiled: August 22, 2011Date of Patent: June 18, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Emile M. Bellott, Dongsheng Bu, James J. Childs, Christopher Lambert, Hubert A. Nienaber, Shirley J. Shi, Zhaolin Wang, Jerome J. Workman, Alex R. Zelenchuk
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Patent number: 8437825Abstract: A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.Type: GrantFiled: July 2, 2009Date of Patent: May 7, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Cristiano Dalvi, Marcelo Lamego, Sean Merritt, Hung Vo, Johannes Bruinsma, Jeroen Poeze, Ferdyan Lesmana, Greg Olsen, Massi Joe E. Kiani
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Patent number: 8428967Abstract: A spot check credit system advantageously includes various embodiments for obtaining authorization or payment for each measurement, groups of measurements, times of measurement or the like. In an embodiment, the system utilizes a server that communicates web pages over a computer network. In an embodiment, the system utilizes a digital communication device such as a photocommunicative key.Type: GrantFiled: May 18, 2011Date of Patent: April 23, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Gregory A. Olsen, Marcelo Lamego, Cristiano Dalvi, Johannes Bruinsma, Jeroen Poeze, Massi Joe E. Kiani
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Patent number: 8423106Abstract: A physiological monitor for determining blood oxygen saturation of a medical patient includes a sensor, a signal processor and a display. The sensor includes at least three light emitting diodes. Each light emitting diode is adapted to emit light of a different wavelength. The sensor also includes a detector, where the detector is adapted to receive light from the three light emitting diodes after being attenuated by tissue. The detector generates an output signal based at least in part upon the received light. The signal processor determines blood oxygen saturation based at least upon the output signal, and the display provides an indication of the blood oxygen saturation.Type: GrantFiled: March 10, 2008Date of Patent: April 16, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Marcelo M. Lamego, Mohamed Diab, Walter M. Weber, Ammar Al-Ali, Joe Kiani
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Patent number: 8388353Abstract: A magnetic connector has a receptacle and a plug. The receptacle has an electromagnet comprising an inner core, an outer core, a coil disposed around the inner core and an air gap defined by the edges of the inner and outer cores. The plug has a plug core and an anchor defined by the plug core edge. The anchor is configured to insert into the air gap as a receptacle socket electrically connects with plug pins. The coil is energized and de-energized so as to assist in the insertion or removal of the anchor from within the air gap and the corresponding connection and disconnection of the socket and pins.Type: GrantFiled: March 10, 2010Date of Patent: March 5, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Massi Joe E. Kiani, Marcelo M. Lamego, Cristiano Dalvi, Hung The Vo
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Patent number: 8385996Abstract: A physiological sensor is adapted to removably attach an emitter assembly and a detector assembly to a fingertip. The emitter assembly is adapted to transmit optical radiation having multiple wavelengths into fingertip tissue. The detector assembly is adapted to receive the optical radiation after attenuation by the fingertip tissue. The sensor has a first shell and a second shell hinged to the first shell. A spring is disposed between the shells and urges the shells together. An emitter pad is fixedly attached to the first shell and configured to retain the emitter assembly. A detector pad is fixedly attached to the second shell and configured to retain the detector assembly. A detector aperture is defined within the detector pad and adapted to pass optical radiation to the detector assembly. A contour is defined along the detector pad and generally shaped to conform to a fingertip positioned over the detector aperture.Type: GrantFiled: April 13, 2009Date of Patent: February 26, 2013Assignee: Cercacor Laboratories, Inc.Inventors: Robert Smith, David Dalke, Ammar Al-Ali, Mohamed Diab, Marcelo Lamego
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Publication number: 20130046204Abstract: A modulated physiological sensor is a noninvasive device responsive to a physiological reaction of a living being to an internal or external perturbation that propagates to a skin surface area. The modulated physiological sensor has a detector configured to generate a signal responsive to the physiological reaction. A modulator varies the coupling of the detector to the skin so as to at least intermittently maximize the detector signal. A monitor controls the modulator and receives an effectively amplified detector signal, which is processed to calculate a physiological parameter indicative of the physiological reaction.Type: ApplicationFiled: August 13, 2012Publication date: February 21, 2013Applicant: CERCACOR LABORATORIES, INC.Inventors: Marcelo Lamego, Cristiano Dalvi, Hung Vo
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Publication number: 20130041591Abstract: In a physiological sensor that estimates a true parameter value by providing a predicted parameter value, multiple measurements are taken to increase the accuracy of the predicted parameter value. The sensor can be reapplied between measurements to decrease the probability of an erroneous prediction caused by sensor misplacement. Some measurements can be discarded before calculating a predicted parameter value. The physiological sensor can have a plurality of modes, with one of the modes corresponding to multiple measurement process.Type: ApplicationFiled: July 13, 2012Publication date: February 14, 2013Applicant: CERCACOR LABORATORIES, INC.Inventor: Marcelo Lamego
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Patent number: 8374665Abstract: A tissue profile wellness monitor measures a physiological parameter, generates a tissue profile, defines limits and indicates when the tissue profile exceeds the defined limits. The physiological parameter is responsive to multiple wavelengths of optical radiation after attenuation by constituents of pulsatile blood flowing within a tissue site. The tissue profile is responsive to the physiological parameter. The limits are defined for at least a portion of the tissue profile.Type: GrantFiled: April 21, 2008Date of Patent: February 12, 2013Assignee: Cercacor Laboratories, Inc.Inventor: Marcelo Lamego