Abstract: Systems, methods and computer-readable media are provided for automatic identification of patients according to near-term risk of ventricular arrhythmias and sudden cardiac death (SCD). Embodiments of the invention are directed to event prediction, risk stratification, and optimization of the assessment, communication, and decision-making to prevent SCD, and in one embodiment take the form of a platform for wearable, mobile, unteathered monitoring devices with embedded decision support. Thus embodiments relate to automatically identifying persons at risk for arrhythmias and SCD through the use of noninvasive, portable, wearable electronic device and sensors equipped with signal-processing software and statistical predictive algorithms that calculate stability-theoretic measures derived from the digital electrocardiogram timeseries acquired by the device.

Abstract: Systems, methods, and computer-readable media are provided for facilitating clinical decision making by directing the emission of computer-generated health-care related recommendations towards contexts in which the recipient will likely find the recommendations salient and will likely welcome them and act upon them. ‘Uptake’ of computer-generated recommendations for diagnostic tests or therapeutic interventions is thereby substantially increased, and ‘alert fatigue’ is substantially decreased. Embodiments of our technology overcome certain drawbacks associated with the prior art by providing a means for ascertaining which decision-support recommendations are likely to be favorably considered by the recipient and acted-upon (recommendation ‘uptake’). System and method embodiments for providing a predicted probability of user uptake of a context-specific system-generated recommendation patient are disclosed herein and for applying that information to decide whether or not to emit the relevant recommendation.

Abstract: A method in a computer system for the review and authentication of clinical laboratory result values is provided. The method includes receiving patient data. The method also includes accessing review criteria. The method further includes comparing the patient data and the review criteria to determine if the patient data should be routed for review. The method further includes routing qualified patient data to a review hierarchy including at least one review queue defined by at least one user.

Abstract: A method in a computer system for preventing atypical clinical events related to information identified by DNA testing a person is provided. The method includes receiving clinical agent information. The method also includes determining if a gene is associated with the clinical agent information, and if so, obtaining a genetic test result value for the associated gene of the person. The method further includes comparing the genetic test result value to a list of polymorphism values associated with an atypical clinical event, and determining whether the genetic test result value correlates to a polymorphism value on the list, and if so, outputting information about the atypical clinical event associated with the polymorphism value.