Patents Assigned to Cerno Bioscience LLC
  • Generation of combinatorial synthetic libraries and screening for proadhesins and nonadhesins
    Patent number: 7132567
    Abstract: One aspect of the present invention relates to compounds, comprising at least two moieties selected from the group consisting of aryl sulfonates and aryl sulfates. A second aspect of the present invention relates to combinatorial libraries of the aforementioned compounds. The present invention also relates to compositions comprising a compound of the present invention. A fourth aspect of the present invention relates to the use of a compound or composition of the present invention in a method for inhibiting bioadhesion to a surface. Another aspect of the present invention relates to the use of a compound or composition of the present invention in a method for enhancing bioadhesion to a surface.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: November 7, 2006
    Assignee: Cerno Biosciences, LLC
    Inventors: Randall S. Alberte, Robert D. Smith
  • Methods for operating mass spectrometry (MS) instrument systems
    Patent number: 6983213
    Abstract: There is provided a method for obtaining at least one calibration filter for a Mass Spectrometry (MS) instrument system. Measured isotope peak cluster data in a mass spectral range is obtained for a given calibration standard. Relative isotope abundances and actual mass locations of isotopes corresponding thereto are calculated for the given calibration standard. Mass spectral target peak shape functions centered within respective mass spectral ranges are specified. Convolution operations are performed between the calculated relative isotope abundances and the mass spectral target peak shape functions to form calculated isotope peak cluster data. A deconvolution operation is performed between the measured isotope peak cluster data and the calculated isotope peak cluster data after the convolution operations to obtain the at least one calibration filter.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: January 3, 2006
    Assignee: Cerno Bioscience LLC
    Inventor: Yongdong Wang
  • Generation of combinatorial synthetic libraries and screening for novel proadhesins and nonadhesins
    Publication number: 20050181455
    Abstract: One aspect of the present invention relates to compounds, comprising at least two moieties selected from the group consisting of aryl sulfonates and aryl sulfates. A second aspect of the present invention relates to combinatorial libraries of the aforementioned compounds. The present invention also relates to compositions comprising a compound of the present invention. A fourth aspect of the present invention relates to the use of a compound or composition of the present invention in a method for inhibiting bioadhesion to a surface. Another aspect of the present invention relates to the use of a compound or composition of the present invention in a method for enhancing bioadhesion to a surface.
    Type: Application
    Filed: February 7, 2005
    Publication date: August 18, 2005
    Applicant: Cerno Biosciences LLC
    Inventors: Randall Alberte, Robert Smith
  • Transgenic plants incorporating traits of Zostera marina
    Patent number: 6841718
    Abstract: The invention provides methods and compositions related to transgenic plants which incorporate genetic traits of the marine eelgrass Zostera marina. These traits include pathogen resistance, which may be conferred by stimulating zosteric acid biosynthesis.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: January 11, 2005
    Assignee: Cerno Biosciences LLC
    Inventors: Randall S. Alberte, Robert Smith