Abstract: An intracranial stent includes a proximal end portion having a first diameter when the intracranial stent is in an expanded state, a distal end portion having a second diameter when the intracranial stent is in the expanded state, a central portion located between the proximal end portion and the distal end portion, the central portion having a third diameter when the intracranial stent is in the expanded state, the third diameter being less than the first diameter and less than the second diameter, and a proximal transition portion extending from the proximal end portion to the central portion, the proximal transition portion having a substantially frustoconical shape such that the proximal transition portion transitions from the first diameter to the third diameter. The intracranial stent also includes a distal transition portion extending from the distal end portion to the central portion, the distal transition portion having a substantially frustoconical shape.

Abstract: A system for treating an intracranial atherosclerotic stenosis in an intracranial blood vessel includes an intracranial stent having a central portion disposed between a proximal portion and a distal portion of the stent, the central portion having a smaller diameter than a diameter of the proximal portion and smaller than a diameter of the distal portion when the stent is in an expanded configuration. The system includes a guiding apparatus having a guidance region, the guidance region having a first radiopaque region, a second radiopaque region, and a radiolucent region. The first radiopaque region and the second radiopaque region are separated by the radiolucent region, and, when the stent is placed on the guidance region, the proximal portion of the stent overlies the first radiopaque region, the central portion of the intracranial stent overlies the radiolucent region, and the distal portion of the intracranial stent overlies the second radiopaque region.

Abstract: An intracranial stent may include one or more rings of struts at a proximal end portion, a distal end portion, a central portion, a proximal transition portion between the proximal end portion and central portion, and a distal transition portion between the distal end portion and central portion. The one or more rings at the central portion may have a diameter that is smaller than a diameter of the one or more rings of struts at the proximal and/or distal end portion. An intracranial stent may include a first ring of connectors connecting a first ring of the one or more rings of struts at the proximal end portion with a second ring of the one or more rings of struts at the proximal transition portion, each connector of the first ring of connectors may include a first curved section, a straight section, and a second curved section.

Abstract: An intracranial stent includes a proximal end portion having a first diameter when the intracranial stent is in an expanded state, a distal end portion having a second diameter when the intracranial stent is in the expanded state, a central portion located between the proximal end portion and the distal end portion, the central portion having a third diameter when the intracranial stent is in the expanded state, the third diameter being less than the first diameter and less than the second diameter, and a proximal transition portion extending from the proximal end portion to the central portion, the proximal transition portion having a substantially frustoconical shape such that the proximal transition portion transitions from the first diameter to the third diameter. The intracranial stent also includes a distal transition portion extending from the distal end portion to the central portion, the distal transition portion having a substantially frustoconical shape.

Abstract: An intracranial stent includes a proximal end portion having a first diameter when the intracranial stent is in an expanded state, a distal end portion having a second diameter when the intracranial stent is in the expanded state, a central portion located between the proximal end portion and the distal end portion, the central portion having a third diameter when the intracranial stent is in the expanded state, the third diameter being less than the first diameter and less than the second diameter, and a proximal transition portion extending from the proximal end portion to the central portion, the proximal transition portion having a substantially frustoconical shape such that the proximal transition portion transitions from the first diameter to the third diameter. The intracranial stent also includes a distal transition portion extending from the distal end portion to the central portion, the distal transition portion having a substantially frustoconical shape.

Abstract: An intracranial stent includes a proximal end portion having a first diameter, a distal end portion having a second diameter, and a central portion located between the proximal end portion and the distal end portion, the central portion having a third diameter, the third diameter being less than the first diameter and less than the second diameter. The intracranial stent includes patterns of interstices, interstices in the central portion having areas that are smaller than areas of the interstices in the proximal end portion and in the distal end portion when the intracranial stent is in the expanded state. The intracranial stent has an unexpanded state in which diameters of the proximal end portion, the distal end portion, and the central portion are smaller than the first diameter, the second diameter, and the third diameter, respectively.

Abstract: An expandable stent to enhance the supply of blood to downstream tissue which is being supplied with blood through a diseased intracranial artery with a stenosis formed therein by plaque with a bore therethrough. The expandable stent includes first and second end portions joined by a central portion. The central portion is configured in the expanded state of the stent to be located in the bore of the stenosis with the first and second end portions abutting non-diseased parts of the artery adjacent the proximal and distal ends of the stenosis for anchoring the stent in the artery. The central portion with the stent in the expanded state is configured to apply a radial outward pressure to the stenosis such that the diameter of the bore of the stenosis is maintained at its current diameter or increased to approximately 50% of the non-diseased parts of the artery.

Abstract: An expandable stent to enhance the supply of blood to downstream tissue which is being supplied with blood through a diseased intracranial artery with a stenosis formed therein by plaque with a bore therethrough. The expandable stent includes first and second end portions and a central portion. The central portion is configured in the expanded state of the stent to contact the stenosis with the first and second end portions anchoring the stent in the artery.

Abstract: An expandable stent (1) to enhance the supply of blood to downstream tissue which is being supplied with blood through a diseased intracranial artery (100) with a stenosis (102) formed therein by plaque with a bore (103) therethrough. The expandable stent (1) comprises first and second end portions (3,4) joined by a central portion (5). The central portion (5) is configured in the expanded state of the stent (1) to be located in the bore (103) of the stenosis (102) with the first and second end portions (3,4) abutting non-diseased parts (104,106) of the artery (100) adjacent the proximal and distal ends (105,107) of the stenosis (102) for anchoring the stent (1) in the artery (100). The central portion (5) with the stent (1) in the expanded state is configured to apply a radial outward pressure to the stenosis (102) such that the diameter of the bore (103) of the stenosis (102) is maintained at its current diameter or increased to approximately 50% of the non-diseased parts (104,106) of the artery (100).

Abstract: An expandable stent to enhance the supply of blood to downstream tissue which is being supplied with blood through a diseased intracranial artery with a stenosis formed therein by plaque with a bore therethrough. The expandable stent includes first and second end portions and a central portion. The central portion is configured in the expanded state of the stent to contact the stenosis with the first and second end portions anchoring the stent in the artery.

Abstract: An expandable stent to enhance the supply of blood to downstream tissue which is being supplied with blood through a diseased intracranial artery with a stenosis formed therein by plaque with a bore therethrough. The expandable stent includes first and second end portions joined by a central portion. The central portion is configured in the expanded state of the stent to be located in the bore of the stenosis with the first and second end portions abutting non-diseased parts of the artery adjacent the proximal and distal ends of the stenosis for anchoring the stent in the artery. The central portion with the stent in the expanded state is configured to apply a radial outward pressure to the stenosis such that the diameter of the bore of the stenosis is maintained at its current diameter or increased to approximately 50% of the non-diseased parts of the artery.

Abstract: An expandable stent (1) to enhance the supply of blood to downstream tissue which is being supplied with blood through a diseased intracranial artery (100) with a stenosis (102) formed therein by plaque with a bore (103) therethrough. The expandable stent (1) comprises first and second end portions (3,4) joined by a central portion (5). The central portion (5) is configured in the expanded state of the stent (1) to be located in the bore (103) of the stenosis (102) with the first and second end portions (3,4) abutting non-diseased parts (104,106) of the artery (100) adjacent the proximal and distal ends (105,107) of the stenosis (102) for anchoring the stent (1) in the artery (100). The central portion (5) with the stent (1) in the expanded state is configured to apply a radial outward pressure to the stenosis (102) such that the diameter of the bore (103) of the stenosis (102) is maintained at its current diameter or increased to approximately 50% of the non-diseased parts (104,106) of the artery (100).