Abstract: The present invention relates to a device for manipulating core body temperature of a human subject by convection and conduction, the device comprising: an open topped liquid carrier vessel adapted to receive a liquid, the liquid carrier vessel having an inlet and an outlet in the base thereof; a removable splash guard for covering the majority of the liquid carrier vessel opening and for resting thereon of a human extremity having an exposed glabrous skin surface; chiller means for cooling liquid received in the vessel and for maintaining the liquid at a predetermined temperature; a jet in the vessel inlet for discharging liquid, or a combination of liquid and air into the liquid carrier vessel; an air valve for controlling the amount of air flowing through the jet; a pump configured to suck liquid from the liquid carrier vessel via the vessel outlet into a suction side of the pump and propel liquid out of a pressure side of the pump into the liquid carrier vessel through the vessel inlet via the chiller mea