Abstract: An efficient sample introduction system and method of use, for accepting liquid sample solutions, nebulizing them to form nebulized sample solution droplets, and introducing the nebulized sample solution droplets to sample analysis systems is disclosed. In the preferred embodiment desolvation of produced nebulized sample solution droplets, and solvent removal, to provide nebulized sample particles is performed prior to entering sample to a sample analysis system. Nebulization of sample solutions is accomplished by use of high efficiency ultrasonic nebulizers and solvent removal is accomplished by use of high efficiency enclosed filter and solvent vapor removal gas flow or low temperature condenser systems. The sample introduction system provides improved sample solution nebulization, desolvation and solvent removal, as well as reduced sample loss and carry-over of sample from one analysis procedure to a subsequent analysis procedure, as compared to other systems which perform a similar overall function.

Abstract: A direct injection micro nebulizer system for use in nebulizing sample solutions in close proximity to sample analysis systems, is disclosed. The present invention offers design features and utility not available in previously known micro nebulizer systems. The present invention, preferrably, provides single piece unibody construction of the primary body element, and construction of all element thereof from nonmetallic, hydrofloric acid resistant materials. The present invention allows easy cleaning and adjustment of element relationships which are necessary to proper operation of direct injection micro nebulizer systems. Use of separate or integrated protective sleeving on otherwise crushable sample solution delivery tubing is also disclosed. Use of the direct injection micro nebulizer with standard and specially designed inductively coupled plasma torches, as well as other sample analysis systems is disclosed.

Abstract: A double pass tandem cooling aerosol condenser apparatus for receiving aerosol from a liquid solution for a specimen sample which has been prepared for injection into an inductively coupled plasma associated with an emission spectra or mass spectrometer comprises inner and outer compartments for circulating a coolant therethrough. The aerosol, comprising solvent and analyte particles, is passed through compartments of the condenser which are interposed between the inner and outer coolant compartment. The temperature of the aerosol compartment is adjusted and controlled such that the solvent particles, which would otherwise quench the inductively coupled plasma, are condensed and stripped from the aerosol leaving a relatively stable, dry aerosol containing the desolvated analyte particles for spectrometric analysis.