Patents Assigned to Cezanne S.A.S.
  • Patent number: 11719697
    Abstract: The present invention relates to an immunoassay method for the detection of Chromogranin A (or fragment(s) thereof) comprising the steps of contacting a sample suspected of comprising Chromogranin A with a first antibody or an antigen-binding fragment or derivative thereof specific for Chromogranin A and a second antibody or an antigen-binding fragment or derivative thereof specific for Chromogranin A under conditions allowing for the formation of a ternary complex between Chromogranin A and the two antibodies or antigen-binding fragments or derivates thereof, and detecting the binding of the two antibodies or antigen-binding fragments or derivates thereof to Chromogranin A. Also provided are antibodies directed against amino acid residues 124 to 144 and 280 to 301 of Chromogranin A and their use in the immunoassay method.
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: August 8, 2023
    Assignee: Cezanne S.A.S.
    Inventors: Pascaline Caruhel, Valerie Rigault, Nadine Guerin
  • Patent number: 10648984
    Abstract: The present invention relates to an immunoassay method for the detection of Chromogranin A (or fragment(s) thereof) comprising the steps of contacting a sample suspected of comprising Chromogranin A with a first antibody or an antigen-binding fragment or derivative thereof specific for Chromogranin A and a second antibody or an antigen-binding fragment or derivative thereof specific for Chromogranin A under conditions allowing for the formation of a ternary complex between Chromogranin A and the two antibodies or antigen-binding fragments or derivates thereof, and detecting the binding of the two antibodies or antigen-binding fragments or derivates thereof to Chromogranin A. Also provided are antibodies directed against amino acid residues 124 to 144 and 280 to 301 of Chromogranin A and their use in the immunoassay method.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: May 12, 2020
    Assignee: Cezanne S.A.S.
    Inventors: Pascaline Caruhel, Valérie Rigault, Nadine Guérin
  • Patent number: 7981621
    Abstract: The present invention relates to the use of matrix metalloproteinase 7 (MMP-7) and/or its precursors and fragments with MMP-7 immunoreactivity, or of circulating anti-MMP-7 antibodies, as humoral biomarkers in diagnostic in vitro methods for the detection, early detection, monitoring and/or prognosis of renal cell carcinoma (RCC) in human patients.
    Type: Grant
    Filed: August 21, 2006
    Date of Patent: July 19, 2011
    Assignee: Cezanne S.A.S.
    Inventors: Bruno Darbouret, Gaiané Sarkissian