Patents Assigned to CHAKRABARTI ADVANCED TECHNOLOGY, LLC
  • System for determination of temperature cycling protocols for polymerase chain reactions; oligonucleotide annealing
    Patent number: 11915794
    Abstract: In one aspect, methods are described herein for enhancing one or more nucleic acid interactions. For example, in some embodiments, methods of enhancing one or more steps of polymerase chain reaction (PCR) are described herein. In some embodiments, the optimal temperature cycling protocol for one or more PCR cycles can be determined according to methods described herein.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: February 27, 2024
    Assignee: Chakrabarti Advanced Technology LLC
    Inventor: Raj Chakrabarti
  • System for determination of temperature cycling protocols for polymerase chain reactions:plymerase extension
    Patent number: 11854667
    Abstract: In one aspect, methods are described herein for enhancing one or more nucleic acid interactions. For example, in some embodiments, methods of enhancing one or more steps of polymerase chain reaction (PCR) are described herein. In some embodiments, the optimal temperature cycling protocol for one or more PCR cycles can be determined according to methods described herein.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: December 26, 2023
    Assignee: Chakrabarti Advanced Technology LLC
    Inventor: Raj Chakrabarti
  • System for determination of temperature cycling protocols for polymerase chain reactions: DNA melting
    Patent number: 11817178
    Abstract: In one aspect, methods are described herein for enhancing one or more nucleic acid interactions. For example, in some embodiments, methods of enhancing one or more steps of polymerase chain reaction (PCR) are described herein. In some embodiments, the optimal temperature cycling protocol for one or more PCR cycles can be determined according to methods described herein.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: November 14, 2023
    Assignee: CHAKRABARTI ADVANCED TECHNOLOGY LLC
    Inventor: Raj Chakrabarti
  • System for determination of temperature cycling protocols for polymerase chain reactions: optimally controlled PCR
    Patent number: 11810647
    Abstract: In one aspect, methods are described herein for enhancing one or more nucleic acid interactions. For example, in some embodiments, methods of enhancing one or more steps of polymerase chain reaction (PCR) are described herein. In some embodiments, the optimal temperature cycling protocol for one or more PCR cycles can be determined according to methods described herein.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: November 7, 2023
    Assignee: Chakrabarti Advanced Technology LLC
    Inventor: Raj Chakrabarti
  • Methods for the design of mechanism-based sirtuin activating compounds
    Patent number: 11459597
    Abstract: The instant invention provides workflows for the design and characterization of mechanism-based sirtuin modulating compounds, including new or improved sirtuin activating compounds. Workflows for the design of mechanism-based sirtuin activating compounds are provided, based on conditions that must be satisfied by activators if they are to exploit the common catalytic mechanism of all sirtuin enzymes and hence increase catalytic efficiency for any sirtuin and any substrate.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: October 4, 2022
    Assignee: CHAKRABARTI ADVANCED TECHNOLOGY LLC
    Inventors: Raj Chakrabarti, Alok Upadhyay, Sudipto Munshi, Suyambu Kesava Vijayan Ramaswamy, Xiangying Guan
  • Methods for the design of mechanism-based sirtuin activating compounds
    Patent number: 11118211
    Abstract: The instant invention provides workflows for the design and characterization of mechanism-based sirtuin modulating compounds, including new or improved sirtuin activating compounds. Workflows for the design of mechanism-based sirtuin activating compounds are provided, based on conditions that must be satisfied by activators if they are to exploit the common catalytic mechanism of all sirtuin enzymes and hence increase catalytic efficiency for any sirtuin and any substrate.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: September 14, 2021
    Assignee: CHAKRABARTI ADVANCED TECHNOLOGY LLC
    Inventors: Raj Chakrabarti, Alok Upadhyay, Sudipto Munshi, Suyambu Kesava Vijayan Ramaswamy, Xiangying Guan
  • System and methods for determination of temperature cycling protocols for polymerase chain reactions
    Patent number: 10861586
    Abstract: In one aspect, methods are described herein for enhancing one or more nucleic acid interactions. For example, in some embodiments, methods of enhancing one or more steps of polymerase chain reaction (PCR) are described herein. In some embodiments, the optimal temperature cycling protocol for one or more PCR cycles can be determined according to methods described herein.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: December 8, 2020
    Assignee: CHAKRABARTI ADVANCED TECHNOLOGY, LLC
    Inventor: Raj Chakrabarti