Abstract: A method of using NC-MRA to generate pelvic veins images and measure rate of blood flow includes subjecting a lay patient to undergo magnetic resonance scan in cooperation with an ECG monitor and a respiration monitor; scanning coronary sections and transverse sections of kidney veins, lower cavity veins, common iliac veins, and external iliac veins to generate two-dimensional images wherein the two-dimensional images use balanced turbo field echo wave sequence; scanning coronary sections of common cardinal veins of abdominal cavity to generate three-dimensional images wherein the three-dimensional images use fast spin-echo short tau inversion recovery wave sequence and sample signals when the ECG monitor monitors myocardial contractility; and using quantification phase-contrast analysis to measure blood flowing through the transverse sections of the veins in a two-dimensional scan.

Abstract: Disclosed herein is a method of quantifying a mutant allele burden of a target gene in a subject. The method includes providing a first plasmid that includes a mutant allele sequence and an internal control sequence, and a second plasmid that includes a wild-type allele sequence and the internal control sequence, and subjecting DNA of the subject to quantitative polymerase chain reaction to measure a mutant allele expression level of the target gene, so as to determine the mutant allele burden of the target gene in the subject based on a standard curve of the mutant allele burden of the target gene created by serial dilution of the first and second plasmids.

Abstract: The present invention provides methods for treating cancer, by administering a therapeutically effective amount of a compound of formula (I), or a pharmaceutically acceptable salt thereof. Also provided are methods for reducing cancer cell metastasis, by administering a therapeutically effective amount of a compound of formula (I) described herein or a pharmaceutically acceptable salt thereof.

Abstract: An apparatus for detecting conductance parameter of high protein body fluid sample is provided. The apparatus includes at least one liquid collection element, and at least two electrodes horizontally aligned in the liquid collection element. Also provided are methods for detecting dehydration in a subject, comprising the steps of measuring the conductance parameter of the saliva of the subject.