Patents Assigned to Charles E. Frosst & Co.
  • Sinister-3,5-disubstituted oxozolidines their preparation and use
    Patent number: 4051144
    Abstract: Preparation of S-3-X-4-(3-substituted amino-2-hydroxypropoxy)-1,2,5-thiadiazole beta adrenergic blocking agents using as starting material an optically active alkalmine in the sinister configuration, or a derivative of said alkamine, which is reacted with an 3-X-4-chloro(or RO-where R is hydrogen or an alkali metal)-1,2,5-thiadiazole. Certain3-morpholino-4-chloro(or RO-)-1,2,5-thiadiazoles and certain alkamines and their preparation also are described. Preferred alkamines are S-3,5-disubstituted oxazolidines.
    Type: Grant
    Filed: December 4, 1974
    Date of Patent: September 27, 1977
    Assignee: Charles E. Frosst & Co.
    Inventors: Leonard M. Weinstock, Roger J. Tull, Dennis M. Mulvey