Patents Assigned to Chembiomed
  • Synthesis of tumor antigenic determinant
    Patent number: 4794176
    Abstract: Processes are provided for the synthesis of the human T-antigenic determinant 2-acetamido-2-deoxy-3-O-(.beta.-D-galactopyranosyl)-.alpha.-D-galactopyran oside containing an .alpha.-O-glycosidically linked bridging arm O--(CH.sub.2).sub.n COR. The determinant is coupled to carrier molecules to form artifical T-antigens, and to insoluble supports to form T-immunoadsorbents. The artificial T-antigen is shown to elicit a delayed type hypersensitivity reaction as a diagnostic for the presence of cancer in humans.
    Type: Grant
    Filed: October 15, 1986
    Date of Patent: December 27, 1988
    Assignee: Chembiomed
    Inventors: Raymond U. Lemieux, Robert M. Ratcliffe, Donald A. Baker