Patents Assigned to ChemGen Corporation
  • Patent number: 7914782
    Abstract: Compositions suitable for oral administration to an animal comprising at least one immune stress-reducing enzyme in an amount effective to decrease the level of positive acute phase protein in an animal, increase the level of negative acute phase protein in an animal, and/or improve animal growth performance is provided, as are methods using such compositions. The compositions include animal feed compositions, liquid compositions other than animal feed, and solid compositions other than animal feed.
    Type: Grant
    Filed: December 14, 2006
    Date of Patent: March 29, 2011
    Assignee: Chemgen Corporation
    Inventors: David M. Anderson, Humg-Yu Hsiao, Lin Liu
  • Patent number: 7723091
    Abstract: Enzymes of a particular class, characterized by the ability to cleave a linkage that effects release of a cell-surface protein or carbohydrate, which does not contain an anti-infection agent, display significant anti-infectious activity. Upon oral administration, these enzymes are effective, for example, in the treatment of digestive tract infections in humans and in animals. In the latter, there are benefits of significantly improved growth rate, feed efficiency, and overall health.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: May 25, 2010
    Assignee: Chemgen Corporation
    Inventors: David M. Anderson, Lin Liu, Humg-Yu Hsiao, Douglas W. Fodge
  • Publication number: 20040223961
    Abstract: Enzymes of a particular class, characterized by the ability to cleave a linkage that effects release of a cell-surface protein or carbohydrate, which does not contain an anti-infection agent, display significant anti-infectious activity. Upon oral administration, these enzymes are effective, for example, in the treatment of digestive tract infections in humans and in animals. In the latter, there are benefits of significantly improved growth rate, feed efficiency, and overall health.
    Type: Application
    Filed: May 28, 2004
    Publication date: November 11, 2004
    Applicant: CHEMGEN CORPORATION
    Inventors: David M. Anderson, Lin Liu, Humg-Yu Hsiao, Douglas W. Fodge
  • Patent number: 6780628
    Abstract: Enzymes of a particular class, characterized by the ability to cleave a linkage that effects release of a cell-surface protein or carbohydrate, which does not contain an anti-infection agent, display significant anti-infectious activity. Upon oral administration, these enzymes are effective, for example, in the treatment of digestive tract infections in humans and in animals. In the latter, there are benefits of significantly improved growth rate, feed efficiency, and overall health.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: August 24, 2004
    Assignee: Chemgen Corporation
    Inventors: David M. Anderson, Lin Liu, Humg-Yu Hsiao, Douglas W. Fodge
  • Patent number: 6162473
    Abstract: A method is provided to increase the efficiency with which monogastric animals utilize low caloric content dietary rations. Addition of a hemicellulase enzyme, such as mannanase, to dietary rations that are not supplemented with concentrated fat, or which contain reduced fat content, increases the efficiency with which monogastric animals utilize the rations.
    Type: Grant
    Filed: November 3, 1998
    Date of Patent: December 19, 2000
    Assignee: Chemgen Corporation
    Inventors: Douglas W. Fodge, Humg-Yu Hsiao
  • Patent number: 5551515
    Abstract: Soil bacteria can be isolated which produce an enzyme capable of catalyzing the degradation of mannan-containing hemicellulose under conditions combining high pH and high temperature. Such bacteria can be cultured or used as sources of genetic information with which to engineer other microorganisms to produce the enzyme. Commercially useful quantities of native or recombinant hemicellulase can thus be produced by cultures consisting essentially of microorganisms capable of producing the enzyme.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: September 3, 1996
    Assignee: Chemgen Corporation
    Inventors: Douglas W. Fodge, David M. Anderson, Thomas M. Pettey
  • Patent number: 5476775
    Abstract: Soil bacteria can be isolated which produce an enzyme capable of catalyzing the degradation of mannan-containing hemicellulose under conditions combining high pH and high temperature. Such bacteria can be cultured or used as sources of genetic information with which to engineer other microorganisms to produce the enzyme. Commercially useful quantities of native or recombinant hemicellulase can thus be produced by cultures consisting essentially of microorganisms capable of producing the enzyme.
    Type: Grant
    Filed: March 16, 1992
    Date of Patent: December 19, 1995
    Assignee: Chemgen Corporation
    Inventors: Douglas W. Fodge, David M. Anderson, Thomas M. Pettey
  • Patent number: 5429828
    Abstract: Soil microorganisms are obtained that produce a hemicellulase which is particularly useful in increasing the available energy content of hemicellulosic foodstuffs. These microorganisms can be cultured per se or can be used as sources of genetic information with which to engineer other microorganisms to produce the enzyme. Thus, commercially useful quantities of native or recombinant hemicellulase can be produced with cultures consisting essentially of microorganisms that produce the enzyme. The hemicellulase can then be employed in a feed composition containing complex carbohydrates which the enzyme degrades, enhancing the nutritional value of the composition.
    Type: Grant
    Filed: July 14, 1992
    Date of Patent: July 4, 1995
    Assignee: Chemgen Corporation
    Inventors: Douglas W. Fodge, David M. Anderson
  • Patent number: 5213972
    Abstract: DNA coding for at least one enzyme that causes the accumulation of a pyrimidine deoxyribonucleoside is used, in conjunction with metabolic mutations or heterologous DNA coding for metabolic enzymes that also increase pyrimidine deoxyribonucleoside production, to engineer cultured cells to express a pyrimidine deoxyribonucleoside (PdN) in recoverable quantities, providing a commercially useful fermentation source for PdNs.
    Type: Grant
    Filed: December 8, 1989
    Date of Patent: May 25, 1993
    Assignee: Chemgen Corporation
    Inventors: Russell J. McCandliss, David M. Anderson
  • Patent number: 5151353
    Abstract: Bacteria that metabolize phenylacetate along a mandelate-to-cis,cis-muconate pathway are disclosed. Bacteria that express the pathway for metabolizing phenylacetate through a mandelate intermediate can be isolated reproducibly by first selecting bacteria that can utilize both L-phenylalanine and mandelate as the sole carbon source and then blocking alternate pathways for the degradation of L-phenylalanine. The activity of selected enzymes along the mandelate-to-cis,cis-muconate pathway can be blocked in these bacteria to effect the accumulation of selected intermediates.
    Type: Grant
    Filed: March 11, 1991
    Date of Patent: September 29, 1992
    Assignee: ChemGen Corporation
    Inventors: Steven D. Geusz, David M. Anderson
  • Patent number: RE38047
    Abstract: Soil microorganisms are obtained that produce a hemicellulase which is particularly useful in increasing the available energy content of hemicellulosic foodstuffs. These microorganisms can be cultured per se or can be used as sources of genetic information with which to engineer other microorganisms to produce the enzyme. Thus, commercially useful quantities of native or recombinant hemicellulase can be produced with cultures consisting essentially of microorganisms that produce the enzyme. The hemicellulase can then be employed in a feed composition containing complex carbohydrates which the enzyme degrades, enhancing the nutritional value of the composition.
    Type: Grant
    Filed: March 8, 2001
    Date of Patent: March 25, 2003
    Assignee: ChemGen Corporation
    Inventors: Douglas W. Fodge, David M. Anderson