Abstract: The present invention relates to reversed phase high-performance liquid chromatography (HPLC) methods useful for the characterisation of glatiramer acetate or similar polypeptide mixtures. The method described herein can distinguish glatiramer acetate from non-conforming copolymers and may be used to choose batches of glatiramer acetate suitable for pharmaceutical use.
Type:
Grant
Filed:
November 15, 2016
Date of Patent:
January 21, 2020
Assignee:
CHEMI, S.P.A.
Inventors:
Maria Lattanzio, Aureliano Gaiassi, Andrea Stevenazzi
Abstract: Purification process of iohexol comprising the treatment of said product with 1-methoxy-2-propanol either alone or mixed with other solvents.
Type:
Grant
Filed:
April 9, 2002
Date of Patent:
May 24, 2005
Assignee:
Chemi, S.p.A.
Inventors:
Stefano Turchetta, Pietro Massardo, Valentina Aromatario