Patents Assigned to Chemiagis, Ltd.
  • Patent number: 6100400
    Abstract: The invention provides a process for the preparation of esters [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid, of the formula (I) ##STR1## wherein X represents a halogen atom and R represents a lower alkyl group comprising reacting:(a) a compound of the formula (II) ##STR2## (b) a compound of the formula (III) ##STR3## and (c) a tertiary amine as a solvent and as an acid scavengerat a temperature of at least 100.degree. C., wherein X is a halogen atom, X' is selected from the group consisting of bromine and chlorine and R is a lower alkyl group.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: August 8, 2000
    Assignee: Chemiagis, Ltd.
    Inventors: Ori Lerman, Erez Gal, Joseph Kaspi