Patents Assigned to Chemic Laboratories, Inc.
  • Compositions comprising folic acid derivatives, their preparations and methods of use
    Patent number: 10590138
    Abstract: Described herein are methods for making folic acid derivatives, intermediates, pharmaceutical compositions and uses thereof.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: March 17, 2020
    Assignee: Chemic Laboratories, Inc.
    Inventors: Gerald S. Jones, Jr., Joseph P. St. Laurent, Scott A. Goodrich
  • Compositions comprising folic acid derivatives, their preparations and methods of use
    Patent number: 10259813
    Abstract: Described herein are methods for making folic acid derivatives, intermediates, pharmaceutical compositions and uses thereof.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: April 16, 2019
    Assignee: Chemic Laboratories, Inc.
    Inventors: Gerald S. Jones, Jr., Joseph P. St. Laurent, Scott A. Goodrich
  • Compositions comprising folic acid derivatives, their preparations and methods of use
    Patent number: 9938280
    Abstract: Described herein are methods for making folic acid derivatives, intermediates, pharmaceutical compositions and uses thereof.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: April 10, 2018
    Assignee: Chemic Laboratories, Inc.
    Inventors: Gerald S. Jones, Jr., Joseph P. St. Laurent, Scott A. Goodrich
  • Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers
    Patent number: 7863025
    Abstract: The present invention provides a novel approach for the preparation of fatty alcohol esters of ?-hydroxy carboxylic acids. In one form of the invention, the target fatty alcohol ester of ?-hydroxy carboxylic acid is produced by converting a lower alkyl ester of ?-hydroxy carboxylic acid into a fatty alcohol ester of ?-hydroxy carboxylic acid via alcoholysis (i.e., transesterification). The transesterification process is an equilibrium reaction, catalyzed chemically (i.e., with acids or bases) or enzymatically, that is shifted in the desired direction to produce the desired product. One preferred way of shifting the reaction in the direction of the desired product is by reducing the concentration of one of the products (e.g., distillation of a lower-boiling alcohol as soon as it is formed). Another preferred way of shifting the reaction in the direction of the desired product is by increasing the concentration of one of the reactants (e.q., adding more of the starting ester).
    Type: Grant
    Filed: October 17, 2005
    Date of Patent: January 4, 2011
    Assignee: Chemic Laboratories, Inc.
    Inventors: Gerald S. Jones, Jr., Joseph P. St. Laurent, Scott A. Goodrich