Patents Assigned to Chemigen
  • Combination therapy using coenzyme Q10 and a caffeic acid-derived ester
    Patent number: 9040579
    Abstract: A pharmaceutical composition containing a mitochondrial electron transport chain enhancer (or an antioxidant) and a compound of formula (I) shown in the specification. This pharmaceutical composition can be used to treat neurodegenerative disorders.
    Type: Grant
    Filed: October 18, 2011
    Date of Patent: May 26, 2015
    Assignee: Chemigen
    Inventor: Yansheng Du
  • Caffeic acid derivatives and their use in improving neuronal cell viability
    Patent number: 8993621
    Abstract: This invention relates to caffeic acid derivatives and improving viability of neuronal cells by contacting neuronal cells by caffeic acid derivatives as shown in the specification.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: March 31, 2015
    Assignee: Chemigen, Inc.
    Inventors: Junyi Liu, Yansheng Du
  • Method for producing caffeic acid phenyl ester and its analogues
    Patent number: 8487125
    Abstract: A method for producing caffeic acid phenyl ester and its analogues, which includes the steps of: (i) reacting, in a solvent, a salt of a compound of formula (II) with an organic halide having the formula X—R2-A2 in the presence of an iodide catalyst having the formula M-I to produce caffeic acid phenyl ester or its analogue, wherein A1, R1, Q, Y, X, R2, and M are defined herein; and (ii) isolating the caffeic acid phenyl ester or its analogue from the solvent.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: July 16, 2013
    Assignee: Chemigen
    Inventors: Junyi Liu, Yansheng Du
  • CAFFEIC ACID DERIVATIVES AND THEIR USE IN IMPROVING NEURONAL CELL VIABILITY
    Publication number: 20120129931
    Abstract: This invention relates to caffeic acid derivatives and improving viability of neuronal cells by contacting neuronal cells by caffeic acid derivatives as shown in the specification.
    Type: Application
    Filed: November 15, 2011
    Publication date: May 24, 2012
    Applicant: ChemiGen
    Inventors: Junyi Liu, Yangsheng Du
  • COMBINATION THERAPY
    Publication number: 20120100122
    Abstract: A pharmaceutical composition containing a mitochondrial electron transport chain enhancer (or an antioxidant) and a compound of formula (I) shown in the specification. This pharmaceutical composition can be used to treat neurodegenerative disorders.
    Type: Application
    Filed: October 18, 2011
    Publication date: April 26, 2012
    Applicant: ChemiGen
    Inventor: Yansheng Du
  • Method for Producing Caffeic Acid Phenyl Ester and Its Analogues
    Publication number: 20110046410
    Abstract: A method for producing caffeic acid phenyl ester and its analogues, which includes the steps of: (i) reacting, in a solvent, a salt of a compound of formula (II) with an organic halide having the formula X—R2-A2 in the presence of an iodide catalyst having the formula M-I to produce caffeic acid phenyl ester or its analogue, wherein A1, R1, Q, Y, X, R2, and M are defined herein; and (ii) isolating the caffeic acid phenyl ester or its analogue from the solvent.
    Type: Application
    Filed: August 19, 2009
    Publication date: February 24, 2011
    Applicant: Chemigen
    Inventors: Junyi Liu, Yansheng Du