Patents Assigned to Chemimage Corporation
  • Patent number: 11741595
    Abstract: A drug screening system and methods of using the same are disclosed. The drug screening system identifies and highlights drugs or other contraband substances enclosed within mailpieces based on score imagery computed from selected wavelengths based on chemical signatures. A wide-field, multispectral short-wave infrared imaging system allows for dissolved, concealed drug screening of mailpieces that improve inspection efficiency and accuracy.
    Type: Grant
    Filed: April 27, 2021
    Date of Patent: August 29, 2023
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Jihang Wang, Evan Krieger, Rick Beideman, Lucas P. Zbur
  • Patent number: 11719985
    Abstract: A non-mechanical liquid crystal tunable filter (LCTF) assembly capable of switching between a multi-conjugate filter mode and a conformal filter mode is described. The non-mechanical LCTF architecture can include a plurality of LCTF components that each comprises a first optical filter comprising a first optical axis, a second optical filter comprising a second optical axis, wherein the second optical axis is rotated 90° relative to the first optical axis, and a first twisted nematic cell positioned between the first optical filter and the second optical filter, the first twisted nematic cell configured to polarize received light by 90° when a voltage is not applied and not polarize the received light when the voltage is applied. The non-mechanical LCTF assembly is configured to switch between a conformal filter mode and a multi-conjugate filter mode based on whether the voltage is applied to each of the plurality of LCTF components.
    Type: Grant
    Filed: July 19, 2022
    Date of Patent: August 8, 2023
    Assignee: ChemImage Corporation
    Inventors: Lei Shi, George Ventouris
  • Patent number: 11699220
    Abstract: Methods, systems, and computer program products of fusing Molecular Chemical Imaging (MCI) and Red Green Blue (RGB) images are disclosed herein. A sample is illuminated with illuminating photons which interact with the sample and are used to form MCI and RGB images. The MCI and RGB images are fused by way of mathematical operations to generate a RGB image with a detection overlay.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: July 11, 2023
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Heather Gomer, Patrick Treado, Jihang Wang
  • Patent number: 11668653
    Abstract: This disclosure is directed to systems and methods for fusing Raman data with biomarker data to identify a disease and/or the progression of the disease. The system disclosed herein may include an illumination source for generating interacted photons from a biological sample and a detector for detecting the interacted photons to generate a Raman data set. A processor is included to fuse the Raman data set with a biomarker data set to identify a disease and/or a disease progression. The instant disclosure further includes a method comprising illuminating a biological sample to generate interacted photons, and detecting the interacted photons to generate a Raman data set. A biomarker data set is obtained from the biological sample, and the Raman data set is fused with the biomarker data set to generate an index score. The index score correlates with one or more of a disease and a disease progression.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: June 6, 2023
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Patrick Treado, Shona Stewart, Aaron Smith, Heather Gomer
  • Patent number: 11607136
    Abstract: Conformal vision with enhanced image processing of the outputted image is incorporated into novel applications. The conformal vision provides enhanced contrast by the combined inclusion of tunable filters and processing of the images that are generated by the detector. Furthermore, novel uses and applications of the conformal vision enable users to make determinations related to their health and wellness utilizing information provided by the conformal vision.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: March 21, 2023
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Matthew Nelson, Thomas Voigt, Maxxwell Chatsko, Patrick Treado, Rebecca Schuler, Shona Stewart, James McGlone, Oksana Klueva, Nathaniel Gomer
  • Patent number: 11598717
    Abstract: Systems for and methods for detecting samples and other compounds of interest are disclosed herein. The system can include an illumination source that is configured to emit light in a variety of different wavelength bands, an optical filter, a camera chip, and an optical path configured to direct the light emitted by the first illumination source at a target and direct the light reflected from the target to the at least one camera chip. The illumination source and the optical filter are transitionable between a first tuning state corresponding to a target tissue and a second tuning state corresponding to a background tissue. The system can be configured to record images at the different tuning states and generate a score image corresponding to the target tissue based on the recorded images.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: March 7, 2023
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Alyssa Zrimsek, Matthew Nelson, Lei Shi, Heather Gomer, Shawna Tazik
  • Patent number: 11568658
    Abstract: A method for multi-target detection and an apparatus for multi-target detection are capable of detecting at least two targets in real time or near real time. The real-time detection or near real time detection can be achieved by at least one of a Recipe Group Approach, an End Member Grouping Approach, and a Pixelated Grouping Based Approach.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: January 31, 2023
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Shawna Tazik, Matthew Nelson, Patrick J. Treado, Ryan J. Priore
  • Patent number: 11525733
    Abstract: The conformal spectral library training method (CSLTM) of the disclosure allows sets of voltages for an optical filter to be calculated by way of a direct calculation without processing large amounts of spectral information, which significantly increases the speed of processing spectral information.
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: December 13, 2022
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Patrick J. Treado, Matthew P. Nelson, Shawna Tazik, Robert C. Schweitzer
  • Patent number: 11499912
    Abstract: In order to avoid friendly fire incidents in the combat theater, novel covert identification systems and methods of identifying friendly forces are provided. The systems include at least a spectroscopic imaging device and a marker that interact with each other by using a synchronized, predetermined filter tuning sequence. The filter tuning sequence enables interacted photons to wavelength hop according to the predetermined tuning sequence. As a result, the covert identification system allows friendly forces to clearly identify each while avoiding detection by enemy forces that employ conventional broadband and night vision sensors.
    Type: Grant
    Filed: January 8, 2020
    Date of Patent: November 15, 2022
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Patrick J. Treado, David W. Caudle, Matthew P. Nelson, Shawna Tazik
  • Patent number: 11486762
    Abstract: Raman spectroscopy data is collected using a Spatial Heterodyne Spectrometer and processed in order to reduce signal noise. The processing of the Raman spectroscopy data includes segmenting generating an interferogram from the Raman spectroscopy data, segmenting the interferogram, determining an estimate of power spectrum density, and averaging the estimates of power spectrum density for each segment to provide an output spectrum. The output spectrum has greatly reduced variance of the individual power measurements, and allows the length of segments to be optimized to balance noise reduction operations and the loss of frequency resolution.
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: November 1, 2022
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Nathaniel Gomer, Heather E. Gomer
  • Patent number: 11307095
    Abstract: Systems for and methods for in situ optimization of tunable light emitting diode sources are disclosed herein. During operation, the systems and methods obtain real-time feedback from an image sensor, and that feedback is used to tune the tunable LEDs. By tuning the tunable LEDs, the best values for the LED spectral output can be selected based on the feedback from the image sensor, and an image with improved contrast is obtained. Alternatively, the amount of time to obtain an image with acceptable contrast is reduced.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: April 19, 2022
    Assignee: Chemimage Corporation
    Inventors: Shawna Tazik, Alyssa Zrimsek, Heather Gomer, Jihang Wang, Patrick J. Treado
  • Patent number: 11293802
    Abstract: Techniques, devices and methods for discriminating a target from a background material without optimizing directly on the target are provided. The devices and methods can generate pass bands of single or multiple wavelengths of variable shape and intensity, and can also select and control the shape of the pass band profiles to improve the detection of targets of interest.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: April 5, 2022
    Assignee: ChemImage Corporation
    Inventors: Alyssa Zrimsek, Heather Gomer, Shawna Tazik
  • Patent number: 11234584
    Abstract: Medical imaging systems for use in conjunction with an endoscope are described. Generally, the medical imaging system includes an illumination source configured to generate illuminating photons. The illuminating photons are transmitted to one or more filters configured to filter a first plurality of illuminating photons and generate a first plurality of filtered photons comprising a first passband wavelength and a second plurality of filtered photons comprising a second passband wavelength. A sample is then illuminated with the first plurality of filtered photons and the second plurality of filtered photons to generate a first plurality of interacted photons and a second plurality of interacted photons. One or more detectors are configured to detect the first plurality of interacted photons and the second plurality of interacted photons and generate one or more image data sets.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: February 1, 2022
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Patrick Treado, Shona Stewart, Matthew P. Nelson
  • Patent number: 11229400
    Abstract: Systems and methods for the detection of calculi in the biliary system are disclosed. The systems include an illumination source, one or more filters that filter a first set of illumination photons and a second set of illumination photons, as well as associated processors and detectors. The system is also designed to generates image data sets and generated information related to the location of the calculi.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: January 25, 2022
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Jeffrey Cohen, Patrick Treado, Shona Stewart, Heather Gomer, Arash Samiei, Alyssa Zrimsek, Jihang Wang
  • Patent number: 11145411
    Abstract: A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: October 12, 2021
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Patrick Treado, Shona Stewart, Heather Kirschner, Ryan Priore, Alan Wilson
  • Patent number: 11120288
    Abstract: The disclosure provides methods, systems, and computer program products for detecting compounds of interest that are deposited on or associated with objects of interest. The compounds of interest are not limited and include drugs, alcohol, cannabis, narcotics, controlled substances as defined by state, federal, or international law, ammonium-based explosives, MGE-based explosives, toxic compounds, organic compounds, inorganic compounds, nerve agents, or biological compounds. The disclosure increases the speed and efficiency of processing hyperspectral images, especially on low-power or portable devices.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: September 14, 2021
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Shashank R. Deshpande, Lucas P. Zbur, Christopher D. Anderson, Patrick J. Treado
  • Patent number: 10779713
    Abstract: The instant disclosure provides for medical imaging systems that may be used in conjunction with an intraoperative medical device, such as an endoscope. Generally, the disclosed medical imaging systems include an illumination source configured to generate illuminating photons for illuminating a biological sample. An optical signal modulator is configured to separate one or more of the illuminating photons and photons that have interacted with the biological sample into a first optical signal having first multi-passband wavelengths and a second optical signal having second multi-passband wavelengths. At least one detector is configured to detect one or more of the first optical signal and the second optical signal and generate at least one image data set. A processor is configured to analyze the at least one image data set. In some embodiments, the processor is configured to differentiate between structures of the biological sample, such as between an ureter and surrounding tissue.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: September 22, 2020
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Patrick Treado, Matthew Nelson, Shona Stewart
  • Patent number: 10317282
    Abstract: The present disclosure provides systems and methods for determining the presence of a target material in a sample. In general terms, the system and method disclosed herein provide collecting interacted photons from a sample having a target material. The interacted photons are passed through a tunable filter to a VIS-NIR detector where the VIS-NIR detector generates a VIS-NIR hyperspectral image representative of the filtered interacted photons. The hyperspectral image of the filtered interacted photons is analyzed by comparing the hyperspectral image of the filtered interacted photons to known hyperspectral images to identify the presence of a target material in a sample. The systems and methods disclosed herein provide easy identification of the presence of a target material in a sample.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: June 11, 2019
    Assignee: ChemImage Corporation
    Inventors: Matthew Nelson, Patrick Treado, Charles Gardner, Andrew Basta
  • Publication number: 20180116494
    Abstract: Medical imaging systems for use in conjunction with an endoscope are described. Generally, the medical imaging system includes an illumination source configured to generate illuminating photons. The illuminating photons are transmitted to one or more filters configured to filter a first plurality of illuminating photons and generate a first plurality of filtered photons comprising a first passband wavelength and a second plurality of filtered photons comprising a second passband wavelength. A sample is then illuminated with the first plurality of filtered photons and the second plurality of filtered photons to generate a first plurality of interacted photons and a second plurality of interacted photons. One or more detectors are configured to detect the first plurality of interacted photons and the second plurality of interacted photons and generate one or more image data sets.
    Type: Application
    Filed: December 9, 2016
    Publication date: May 3, 2018
    Applicant: ChemImage Corporation
    Inventors: Patrick TREADO, Shona STEWART
  • Patent number: 9658104
    Abstract: A system and method for analyzing unknown materials on surfaces including, but not limited to, chemical materials, biological materials, hazardous materials, drug materials, and non-threat materials using SWIR and/or extended range SWIR hyperspectral and spectroscopic techniques. A system comprising a collection optics, a tunable filter, and a first detector for generating a test data set representative of the unknown sample. A second detector, comprising a visible imaging device, may be configured to operate in a scanning mode to locate areas of interest for further interrogation using SWIR. A method comprising generating a SWIR test data set representative of the unknown sample and analyzing the unknown sample to detect, identify and/or distinguish an unknown material as a known material. This analysis may be achieved by comparing the test data set to a reference data set using at least one chemometric technique.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: May 23, 2017
    Assignee: ChemImage Corporation
    Inventors: Patrick J. Treado, Matthew Nelson, Charles W. Gardner