Patents Assigned to Chemisch Pharmazeutische Forschungsgesellschaft m.b.H.
  • Patent number: 5679678
    Abstract: Thienothiazine derivatives of the formula ##STR1## are provided. These derivatives are useful for the treatment of inflammation and pain.
    Type: Grant
    Filed: December 14, 1994
    Date of Patent: October 21, 1997
    Assignee: Chemisch Pharmazeutische Forschungsgesellschaft m.b.H.
    Inventors: Dieter Binder, Josef Weinberger, Michael Pyerin
  • Patent number: 5527796
    Abstract: Thienothiazine derivatives of the formula ##STR1## in which X denotes a single bond, a straight chain or branched carbon chain having 1-12 C-atoms in the chain, it being possible for this chain to contain one or more double or triple bonds and/or two or more heteroatoms, Y denotes a single bond, and R denotes a monocyclic or polycyclic, optionally partly hydrogenated aryl, heteroaryl, arlyoxy, arylaza, heteroarylaza, arylthio or heteroarylthio radical which can optionally be substituted by lower alkyl, mono- or poyhalogenated lower alkyl, perfluorinated lower alkyl, alkoxy or halogen, and their use.
    Type: Grant
    Filed: February 18, 1994
    Date of Patent: June 18, 1996
    Assignee: Chemisch Pharmazeutische Forschungsgesellschaft m.b.H.
    Inventors: Dieter Binder, Josef Weinberger
  • Patent number: 5254574
    Abstract: Tetrazole derivatives of the formula ##STR1## in which R.sub.1 denotes a saturated or unsaturated, straight-chain or branched (C.sub.1 -C.sub.6) alkyl radical and R.sub.2 denotes methyl or ethyl, and their pharmaceutically usable salts.
    Type: Grant
    Filed: December 31, 1991
    Date of Patent: October 19, 1993
    Assignee: Chemisch Pharmazeutische Forschungsgesellschaft m.b.H.
    Inventors: Dieter Binder, Josef Weinberger, Andreas Koch
  • Patent number: 5086180
    Abstract: Sulphamoylathiophenes of the formula ##STR1## in which Y denotes O or S,A denotes a single bond or a straight-chain or branched alkylene group having 1-5 carbon atoms,R.sub.1 denotes methyl or trifluoromethyl andR.sub.2 denotes hydrogen or a group COOH or COOR.sub.3, in whichR.sub.3 represents (C.sub.1 -C.sub.4)-alkyl,and, in the case in which R.sub.2 denotes a group COOH, their pharmaceutically tolerable salts, a process for their preparation, pharmaceutical preparations which contain these compounds and their use in medicaments as leukotriene antagonists for the treatment of asthma and allergies.
    Type: Grant
    Filed: June 15, 1990
    Date of Patent: February 4, 1992
    Assignee: Chemisch Pharmazeutische Forschungsgesellschaft m.b.H.
    Inventors: Dieter Binder, Franz Rovenszky, Norman Brunner, Hubert P. Ferber
  • Patent number: 5077307
    Abstract: Thienopyran derivatives of the general formula ##STR1## in which the radial ##STR2## denotes one of the formulae ##STR3## R denotes hydrogen or a radical --CN, --CHO, --CH.dbd.NOH, --CONH.sub.2 or --COOR.sub.1,R.sub.1 denotes the radical (C.sub.1 -C.sub.4)-alkyl and n denotes an integer 3, 4 or 5, and a process for their preparation, pharmaceutical preparation and their use for the treatment of diseases which can be cured by activation of membrane K.sup.+ channels, such as high blood pressure and asthma.
    Type: Grant
    Filed: June 13, 1990
    Date of Patent: December 31, 1991
    Assignee: Chemisch Pharmazeutische Forschungsgesellschaft m.b.H.
    Inventors: Dieter Binder, Franz Rovenszky, Josef Weinberger, Hubert P. Ferber
  • Patent number: 4978671
    Abstract: The invention relates to novel thieno-(3',4'-4,5)imidazo(2,1-b)thiazole derivatives of the formula ##STR1## in which R.sub.1 denotes hydrogen, halogen or CF.sub.3 andR.sub.2 denotes hydrogen or C.sub.1 -C.sub.4 alkyl and, in the case in which R.sub.2 denotes hydrogen, their pharmaceutically utilizable salts, a process for the preparation of these compounds and their use for the treatment of cancer or rheumatoid arthritis caused by a defective immune system.
    Type: Grant
    Filed: August 30, 1989
    Date of Patent: December 18, 1990
    Assignee: Chemisch Pharmazeutische Forschungsgesellschaft m.b.H.
    Inventors: Dieter Binder, Franz Rovenszky, Hubert P. Ferber