Abstract: The present invention provides topical formulations having an autophagy stimulating and/or heme oxygenase and activating/triggering effect on human skin for cosmetic and pharmaceutical use. Furthermore, the present invention provides topical formulations that trigger production of VEGF-C, reduce melanin synthesis and boost energy and cell function. Moreover, the present invention provides a new process for producing a herbal composition comprising a mixture of components of Bellis perennis L. and optionally Hieracium pilosella by aqueous extraction and the herbal composition comprising a mixture of components produced by the process of the present invention. The pharmaceutical formulations according to the present invention may be used for the treatment or prevention of dark circles under the eye and/or puffy eyes. The herbal composition according to the present invention may also be used in a cosmetic formulation for the cosmetic treatment or prevention of dark circles under the eye and/or puffy eyes.

Abstract: The present invention relates to an active agent complex of extracts of Poria cocos and a species of the genus Phragmites, in particular Phragmites kharka (also Phragmites karka), formulations comprising said active agent complex as well as to the use of the formulations of the invention for the strengthening, maintenance and quicker restoration of epidermal integrity.

Abstract: The present invention pertains to topical formulations having a depigmenting effect on human skin for cosmetic and pharmaceutical use. Moreover the present invention also provides a new process for producing an extract of Bellis perennis L. by aqueous extraction comprising fractionation and electrolyte exchange and an extract produced by the process of the present invention.

Abstract: The invention relates to cosmetic compositions for topical application for counteracting UV radiation induced skin damage comprising as active substances a first component which comprises inactivated bacteria selected from the group consisting of the genus Bifidobacterium, Actinomycetaceae, Propionimycetaceae, Lactobacillaceae and Coryneform bacteria and a second component which comprises an extract of plant extracellular matrix. Preferably, the plant extracellular matrix is selected from the group consisting of glycoproteins, carbohydrate polymers and arabinogalactan proteins. Processes for using the cosmetic compositions are also described.

Abstract: The invention provides compositions for the repair and remodelling of sun damaged and aged skin. The composition comprises a component of plant extracellular matrix extract in substantially native conformation, and can include a cosmetic carrier. In particular, the composition can include a glycoprotein of a plant extracellular matrix composition, a carbohydrate polymer of plant extracellular matrix composition, and mixtures thereof, each in substantially native conformation. Plant extracellular matrix extracts from Kudzu and maize are obtained.

Abstract: A cosmetic agent for remodeling and repairing the basement membrane of aging human skin and/or human skin damaged, for example, by ultraviolet radiation. The agent contains the essential components of the extracellular connective tissue matrix in native form and in physiological proportions. The components are obtained from mammals.