Patents Assigned to Chi-Mei Medical Center
  • Publication number: 20230106048
    Abstract: The present disclosure provides a method for ameliorating and/or treating dengue virus infection or symptoms of dengue virus infection comprising administrating a pharmaceutical composition to the subject, wherein the pharmaceutical composition comprises an effective amount of 2,6-diisopropylphenol and optionally a pharmaceutically acceptable carrier.
    Type: Application
    Filed: October 1, 2021
    Publication date: April 6, 2023
    Applicant: CHI MEI MEDICAL CENTER
    Inventors: Chung-Hsi HSING, Chiou-Feng LIN
  • Patent number: 11288801
    Abstract: An establishing method of a retinal layer thickness detection model includes following steps. A reference database is obtained, and an image pre-processing step, a feature selecting step, a training step and a confirming step are performed. The reference database includes reference optical coherence tomographic images. In the image pre-processing step, the reference optical coherence tomographic images are duplicated and cell segmentation lines of retinal layers are marked to obtain control optical coherence tomographic images. In the feature selecting step, the reference optical coherence tomographic images are analyzed to obtain reference image features. The training step is to train with the reference image features and obtain the retinal layer thickness detection model.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: March 29, 2022
    Assignees: NATIONAL CHIN-YI UNIVERSITY OF TECHNOLOGY, CHI MEI MEDICAL CENTER
    Inventors: Yue-Jing He, Ching-Ping Chang, Shu-Chun Kuo, Kao-Chang Lin
  • Patent number: 10912531
    Abstract: A system for creating a three-dimensional (3D) bone image of a bone is used with a 3D bone model of the bone that includes a plurality of bony landmarks. The system includes a 3D scanning device to scan the bone and generate a bone contour image, and an image processing device. The image processing device processes the 3D bone model to obtain a plurality of spatial locations respectively of the bony landmarks, and processes the bone contour image to identify a plurality of features that correspond respectively with the bony landmarks and to obtain a plurality of spatial locations respectively of the features. The image processing device performs image registration for the 3D bone model and the bone contour image, so as to create the 3D bone image by proportionally overlapping the 3D bone model and the bone contour image.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: February 9, 2021
    Assignee: Chi Mei Medical Center
    Inventor: Ching-Feng Liu
  • Patent number: 9381012
    Abstract: An illuminated surgical retractor system includes a surgical retractor and at least one illumination device. The surgical retractor includes an outer ring, a light-transmissive hollow inner ring, and a tubular retraction membrane which extends between the output ring and the inner ring and which has a first open end connected to and spread open by the outer ring and a second open end connected to and spread open by the inner ring. The illumination device is disposed in the inner ring and is operable to emit a light beam. The illumination device includes a magnetic component which is responsive to an applied magnetic field to cause the illumination device to change a direction in which the light beam is emitted.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: July 5, 2016
    Assignee: Chi Mei Medical Center
    Inventor: Ying-Chieh Su
  • Patent number: 9314504
    Abstract: The invention relates to a novel use of the members of the IL-10 cytokine family in wound healing. Particularly, the invention relates to the use of the member of the IL-10 cytokine family in the promotion of the proliferation and the migration of keratinocyte cells in wound healing.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: April 19, 2016
    Assignees: TAIPEI MEDICAL UNIVERSITY, CHI MEI MEDICAL CENTER
    Inventors: Ching-Hsi Hsing, Ching Hua Yeh, Li-Yun Wang, Ding Ping Sun
  • Patent number: 9164077
    Abstract: The present invention discloses a biological detection device and a detecting method. The biological detection device comprises a substrate, an electric field unit, a liquid crystal/polymer composite film (LCPCF), a power supply, a processing unit, and an image sensor. Because of the electrically tunable orientations of the liquid crystal (LC) director anchored among the polymer grains, the wettability of the LCPCF changes with an applied electric field. As a result, we can manipulate a blood droplet on the LCPCF by a wettability gradient owing to the distribution of LC directors on the LCPCF. The motion states of the blood droplet can be related to the various qualities of the blood, and finally determines the health of the test sample. The change of contact angle of blood on LCPCF and the blood droplet motion on LCPCF indicate the concentration of TG and the concentration of HDL.
    Type: Grant
    Filed: August 27, 2012
    Date of Patent: October 20, 2015
    Assignees: NATIONAL CHIAO TUNG UNIVERSITY, CHI MEI MEDICAL CENTER
    Inventors: Yi-Hsin Lin, Wei-Lin Chu, Li-Ching Wu
  • Publication number: 20140271539
    Abstract: The invention relates to a novel use of the members of the IL-10 cytokine family in wound healing. Particularly, the invention relates to the use of the member of the IL-10 cytokine family in the promotion of the proliferation and the migration of keratinocyte cells in wound healing.
    Type: Application
    Filed: March 14, 2013
    Publication date: September 18, 2014
    Applicants: CHI MEI MEDICAL CENTER, TAIPEI MEDICAL UNIVERSITY
    Inventor: Chung-Hsi HSING
  • Publication number: 20140069423
    Abstract: A tracheal tube includes an airway tubular body, an inflatable cuff disposed on the airway tubular body, a suction conduit extending along the airway tubular body to terminate at a suction opening, and a guiding unit disposed on the airway tubular body and adjacent to the suction opening. The guiding unit includes at least one guiding member having a plurality of ribs. Each two adjacent ones of the ribs define a guiding groove that extends toward the suction opening and that terminates at a confluent region in fluid communication with the suction opening so as to guide secretions in the trachea to the suction opening.
    Type: Application
    Filed: September 5, 2013
    Publication date: March 13, 2014
    Applicant: Chi Mei Medical Center
    Inventor: Ying-Chieh SU
  • Publication number: 20140058234
    Abstract: A device adapted for insertion into one or more of an esophagus, a stomach, an intestine and a colon for detecting a blood-oxygen level associated with at least one mucous membrane region in said one or more of the esophagus, the stomach, the intestine and the colon is disclosed. The device includes a flexible and elongated main body, and a blood oxygen level detecting unit. The blood oxygen level detecting unit includes one or more blood oxygen level detecting modules disposed on the main body and capable of generating one or more signals associated with the blood oxygen level(s) of one or more mucous membrane regions nearby the blood oxygen level detecting module(s).
    Type: Application
    Filed: August 21, 2013
    Publication date: February 27, 2014
    Applicant: Chi Mei Medical Center
    Inventors: Ying-Chieh Su, Jui-Wen Pan, Bor-Shyh Lin
  • Patent number: 8636658
    Abstract: A surgical retractor includes an outer ring unit, a tubular retraction membrane made of a resilient material and including an inner surface defining a passageway, and a lighting unit. The tubular retraction membrane has an outer tubular end connected to the outer ring unit and rollable about the outer ring unit. The lighting unit is connected to an inner tubular end of the retraction membrane and includes a light-emitting ring, and a heat-dissipation ring in contact with the light-emitting ring.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: January 28, 2014
    Assignee: Chi Mei Medical Center
    Inventors: Ying-Chieh Su, Chao-Kun Chen, Yao Fong
  • Publication number: 20130018230
    Abstract: A surgical retractor includes an outer ring unit, a tubular retraction membrane made of a resilient material and including an inner surface defining a passageway, and a lighting unit. The tubular retraction membrane has an outer tubular end connected to the outer ring unit and rollable about the outer ring unit. The lighting unit is connected to an inner tubular end of the retraction membrane and includes a light-emitting ring, and a heat-dissipation ring in contact with the light-emitting ring.
    Type: Application
    Filed: July 10, 2012
    Publication date: January 17, 2013
    Applicant: CHI MEI MEDICAL CENTER
    Inventors: Ying-Chieh SU, Chao-Kun CHEN, Yao FONG
  • Publication number: 20130012770
    Abstract: A combined retractor and endoscope system includes a retraction ring and an endoscope unit. The retraction ring includes a tubular inner surface defining a passageway. The endoscope unit includes a flexible arm that can be positioned stably and moved between an edge of an incision and an outer peripheral surface of the retraction ring, and a camera attached to one end of the flexible arm. In a preferred embodiment, the flexible arm has a flexible outer tube body incorporating a support strip that can be bent together with the outer tube body to retain a bent configuration of the outer tube body.
    Type: Application
    Filed: July 2, 2012
    Publication date: January 10, 2013
    Applicant: Chi Mei Medical Center
    Inventor: YING-CHIEH SU
  • Publication number: 20110208255
    Abstract: An introducer device is for use in Nuss procedure to guide a steel bar in retrieving an insertion route which passes through and between a patient's sternum and heart. The introducer device includes an elongated introducer body and an ultrasonic probe. The introducer body extends in a lengthwise direction to terminate at a leading tip end for coupling the concave steel bar to retrieve the insertion route, and a grip end opposite to the leading tip, and has a curve segment configured to establish the insertion route when the leading tip end is led to pass through and between the sternum and the heart. The curve segment has a concave sternum-side surface and a convex heart-side surface. The ultrasonic probe is coupled to the leading tip end to transmit ultrasonic waves towards the heart and to receive reflected ultrasonic waves traveling from the heart when passing through and between the sternum and the heart.
    Type: Application
    Filed: October 18, 2010
    Publication date: August 25, 2011
    Applicant: CHI MEI MEDICAL CENTER
    Inventor: Ying-Chieh Su
  • Publication number: 20110208237
    Abstract: A forceps for pathological diagnosis includes first and second proximate arm segments including finger-operable grip ends that are movable towards or away from each other, first and second distal arm segments including grasping-jaw ends that are movable towards or away from each other, a coupling member disposed to bring the relative movement between the first and second proximate arm segments into synchronization with that between the first and second distal arm segments, an ultrasonic probe mounted to the grasping-jaw end of the first distal arm segment, and adapted to transmit ultrasonic waves towards a target tissue that is clamped between the grasping-jaw ends and to receive reflected ultrasonic waves traveling from the target tissue, and a shielding member disposed on the grasping-jaw end of the second distal arm segment, and capable of partially reflecting ultrasonic waves transmitting through the target tissue.
    Type: Application
    Filed: October 4, 2010
    Publication date: August 25, 2011
    Applicant: CHI MEI MEDICAL CENTER
    Inventor: Ying-Chieh Su
  • Publication number: 20090048432
    Abstract: This invention features an antibody specifically binding to human IL-20 (e.g., mAb 7E and a equivalent thereof) and its use in treating an IL-20 associated inflammatory disease, such as atherosclerosis, RA, psoriasis, psoriatic arthritis, bacteria-induced gastric ulcer, and acute renal failure.
    Type: Application
    Filed: September 26, 2008
    Publication date: February 19, 2009
    Applicant: Chi Mei Medical Center of Taiwan
    Inventor: Ming-Shi Chang
  • Patent number: 7435800
    Abstract: Antibody to human IL-20 protein, a method for generation thereof and cells producing this antibody are disclosed. The antibody of the present invention has specificity to neutralizing hIL-20W-induced CPAE proliferation activity, and is useful for treating IL-20-induced inflammation, such as artheriosclerosis and rheumatoid arthritis.
    Type: Grant
    Filed: March 2, 2006
    Date of Patent: October 14, 2008
    Assignee: Chi-Mei Medical Center
    Inventor: Ming-Shi Chang