Patents Assigned to Chiayi Chang Gung Memorial Hospital
  • Method of preventing or treating osteoporosis by neddylation inhibitor
    Patent number: 10285994
    Abstract: Disclosed herein is a method of preventing and/or treating abnormal bone resorption and/or osteoporosis in a subject in need thereof. The method comprises administering to the subject an effective amount of an inhibitor on inhibiting neddylation. According to some embodiments of the present disclosure, the inhibitor on inhibiting neddylation is a NAE inhibitor, which includes but is not limited to, MLN4924.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: May 14, 2019
    Assignees: CHANG GUNG UNIVERSITY, CHIAYI CHANG GUNG MEMORIAL HOSPITAL
    Inventors: Chung-Sheng Shi, Meng-Huang Wu, Kuo-Ti Peng
  • METHOD OF PREVENTING OR TREATING OSTEOPOROSIS BY NEDDYLATION INHIBITOR
    Publication number: 20180303833
    Abstract: Disclosed herein is a method of preventing and/or treating abnormal bone resorption and/or osteoporosis in a subject in need thereof. The method comprises administering to the subject an effective amount of an inhibitor on inhibiting neddylation. According to some embodiments of the present disclosure, the inhibitor on inhibiting neddylation is a NAE inhibitor, which includes but is not limited to, MLN4924.
    Type: Application
    Filed: April 20, 2018
    Publication date: October 25, 2018
    Applicants: Chang Gung University, Chiayi Chang Gung Memorial Hospital
    Inventors: Chung-Sheng SHI, Meng-Huang WU, Kuo-Ti PENG