Abstract: Described herein are methods and compositions for treating asthma or an allergic disease. Aspects of the invention relate to administering to a subject an agent that targets Notch4. In one embodiment, the agent is an anti-Notch4 antibody.
Type:
Application
Filed:
March 15, 2019
Publication date:
September 9, 2021
Applicant:
THE CHIDLREN'S MEDICAL CENTER CORPORATION
Inventors:
Talal Amine CHATILA, Hani HARB, Mingcan XIA, Amir MASSOUD
Abstract: Streptococcus pneumoniae is a major health concern, especially in very young, elderly, or immunocompromised patients. The present disclosure provides, inter alia, certain highly effective vaccines and pharmaceutical compositions in Streptococcus pneumoniae. The antigens may be used therapeutically or prophylactically.
Type:
Grant
Filed:
June 29, 2010
Date of Patent:
October 23, 2018
Assignees:
Genocea Biosciences, Inc., Chidlren's Medical Center Corporation